Michielsen B, Leys A, Van Damme B, Missotten L
Department of Ophthalmology, K.U. Leuven, Belgium.
Doc Ophthalmol. 1990;76(3):219-29. doi: 10.1007/BF00142681.
Chronic membranoproliferative glomerulonephritis type II (dense deposit disease) is a renal disease characterized by dense deposits in the glomerular and tubular basement membranes. We report a retinopathy with diffuse retinal pigment alterations in 11 out of 12 patients with this disease. Four of the eleven patients also presented disciform macular detachment and choroidal neovascularisation. The lesions were observed at the earliest 1 year after the diagnosis of the renal disease. In a control group of 17 patients with chronic membranoproliferative glomerulonephritis type I none of the patients presented similar fundus lesions.
II型慢性膜增生性肾小球肾炎（致密物沉积病）是一种以肾小球和肾小管基底膜出现致密物沉积为特征的肾脏疾病。我们报告了12例患有该疾病的患者中有11例出现了伴有弥漫性视网膜色素改变的视网膜病变。11例患者中有4例还出现了盘状黄斑脱离和脉络膜新生血管形成。这些病变最早在肾病诊断后1年被观察到。在一个由17例I型慢性膜增生性肾小球肾炎患者组成的对照组中，没有患者出现类似的眼底病变。
