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局部应用的左布诺洛尔不会引起角膜内皮的变化。

Topically applied levobunolol does not cause changes in the corneal endothelium.

作者信息

Fusco R, Del Prete A, Gravina A, Nieto G

机构信息

2nd Medicine School Naples, 2nd Eye Clinic Prof. Mario D'Esposito, Napoli, Italy.

出版信息

Doc Ophthalmol. 1990;76(3):273-7. doi: 10.1007/BF00142686.

DOI:10.1007/BF00142686
PMID:2103529
Abstract

The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. The untreated fellow eye served as a control. The number of endothelial cells, determined with a McIntyre eyepiece and an Eisner's contact lens, was not affected by levobunolol therapy. In addition, the morphology of the cell did not appear to be affected by the drug.

摘要

对10例高眼压症患者在局部使用左布诺洛尔治疗前、治疗期间及治疗4个月后进行角膜内皮检查。未治疗的对侧眼作为对照。使用麦金太尔目镜和艾斯纳接触镜测定的内皮细胞数量未受左布诺洛尔治疗的影响。此外,细胞形态似乎也未受该药物影响。

相似文献

1
Topically applied levobunolol does not cause changes in the corneal endothelium.局部应用的左布诺洛尔不会引起角膜内皮的变化。
Doc Ophthalmol. 1990;76(3):273-7. doi: 10.1007/BF00142686.
2
Efficacy and safety of once-daily levobunolol for glaucoma therapy.
Can J Ophthalmol. 1989 Feb;24(1):2-6.
3
Levobunolol and metipranolol: comparative ocular hypotensive efficacy, safety, and comfort.左旋布诺洛尔和美替洛尔:眼压降低效果、安全性及舒适度的比较
Br J Ophthalmol. 1987 Apr;71(4):250-3. doi: 10.1136/bjo.71.4.250.
4
A comparison of the ocular hypotensive efficacy and systemic safety of 0.5% levobunolol and 2% carteolol.0.5%左布诺洛尔与2%卡替洛尔的降眼压疗效及全身安全性比较。
Ophthalmologica. 1994;208(1):32-6. doi: 10.1159/000310446.
5
Levobunolol. A three-month efficacy study in the treatment of glaucoma and ocular hypertension.
Arch Ophthalmol. 1985 Mar;103(3):375-8. doi: 10.1001/archopht.1985.01050030071024.
6
Levobunolol compared with timolol for the long-term control of elevated intraocular pressure.
Arch Ophthalmol. 1985 Mar;103(3):379-82. doi: 10.1001/archopht.1985.01050030075025.
7
Efficacy of twice-daily levobunolol in the treatment of elevated intraocular pressure.每日两次使用左布诺洛尔治疗眼压升高的疗效。
Can J Ophthalmol. 1988 Jun;23(4):168-70.
8
A dose-response study of the effect of levobunolol on ocular hypertension.左旋布诺洛尔对高眼压症影响的剂量反应研究。
Am J Ophthalmol. 1983 Feb;95(2):229-32. doi: 10.1016/0002-9394(83)90018-1.
9
Corneal endothelial changes in ocular hypertensive individuals after long-term unilateral treatment with timolol.噻吗洛尔长期单侧治疗高眼压个体后的角膜内皮变化
Am J Ophthalmol. 1990 Sep 15;110(3):309-10. doi: 10.1016/s0002-9394(14)76353-6.
10
Levobunolol vs timolol for open-angle glaucoma and ocular hypertension.左旋布诺洛尔与噻吗洛尔治疗开角型青光眼和高眼压症的比较
Am J Ophthalmol. 1985 Jan 15;99(1):11-7. doi: 10.1016/s0002-9394(14)75859-3.

本文引用的文献

1
Adverse reactions from timolol administration.噻吗洛尔给药引起的不良反应。
Ophthalmology. 1980 May;87(5):447-50. doi: 10.1016/s0161-6420(80)35215-9.
2
Effects of timolol on bovine corneal endothelial cultures.
Arch Ophthalmol. 1981 Apr;99(4):660-3. doi: 10.1001/archopht.1981.03930010660012.
3
Levobunolol compared with timolol for the long-term control of elevated intraocular pressure.
Arch Ophthalmol. 1985 Mar;103(3):379-82. doi: 10.1001/archopht.1985.01050030075025.
4
Levobunolol. A three-month efficacy study in the treatment of glaucoma and ocular hypertension.
Arch Ophthalmol. 1985 Mar;103(3):375-8. doi: 10.1001/archopht.1985.01050030071024.
5
Levobunolol and metipranolol: comparative ocular hypotensive efficacy, safety, and comfort.左旋布诺洛尔和美替洛尔:眼压降低效果、安全性及舒适度的比较
Br J Ophthalmol. 1987 Apr;71(4):250-3. doi: 10.1136/bjo.71.4.250.