Dipartimento di Biologia, Via San Zeno, 37-39, 56127 Pisa, Pisa University, Italy.
Res Microbiol. 2010 Nov;161(9):743-9. doi: 10.1016/j.resmic.2010.10.007. Epub 2010 Oct 28.
When propagated on solid surfaces, Bacillus cereus can produce differentiated swarm cells under a wide range of growth conditions. This behavioural versatility is ecologically relevant, since it allows this bacterium to adapt swarming to environmental changes. Swarming by B. cereus is medically important: swarm cells are more virulent and particularly prone to invade host tissues. Characterisation of swarming-deficient mutants highlights that flagellar genes as well as genes governing different metabolic pathways are involved in swarm-cell differentiation. In this review, the environmental and genetic requirements for swarming and the role played by swarm cells in the virulence this pathogen exerts will be outlined.
当在固体表面上繁殖时，蜡状芽孢杆菌可以在广泛的生长条件下产生分化的游动细胞。这种行为的多功能性在生态学上是相关的，因为它允许这种细菌适应环境变化的游动。蜡状芽孢杆菌的游动对医学很重要：游动细胞更具毒性，特别容易侵入宿主组织。对游动缺陷突变体的特征分析突出了鞭毛基因以及控制不同代谢途径的基因都参与了游动细胞的分化。在这篇综述中，将概述游动的环境和遗传要求以及游动细胞在该病原体毒性中所起的作用。
