Department of Psychology, Vanderbilt University, 111 21st Avenue South, Nashville, TN 37203, USA.
Behav Ther. 2010 Dec;41(4):475-90. doi: 10.1016/j.beth.2009.11.005. Epub 2010 May 13.
The present investigation examines the incremental association between disgust propensity and sensitivity and contamination-based obsessive-compulsive disorder (OCD) symptoms. Structural equation modeling in Study 1 indicated that general disgust was related to contamination fear even when controlling for negative affect in a nonclinical sample. Evidence was also found for a model in which the effect of negative affect on contamination fear is mediated by general disgust. Study 1 also showed that both disgust sensitivity and disgust propensity uniquely predicted contamination fear when controlling for negative affect. Growth curve analyses in Study 2 indicated that higher baseline contamination fear is associated with less reduction in contamination fear over a 6-week period as disgust sensitivity increases even when controlling for negative affect. Lastly, disgust propensity was associated with concurrent levels of excessive washing symptoms among patients with OCD in Study 3 when controlling for depression. Implications of these findings from nonclinical, analogue, and clinical samples for future research on the specificity of disgust-related vulnerabilities in the etiology of contamination concerns in OCD are discussed.
本研究考察了厌恶倾向和敏感性与基于污染的强迫症(OCD)症状之间的增量关联。研究 1 中的结构方程模型表明,即使在非临床样本中控制负性情绪的情况下,一般厌恶也与污染恐惧有关。也有证据表明,在这个模型中,负性情绪对污染恐惧的影响是由一般厌恶介导的。研究 1 还表明,当控制负性情绪时,厌恶敏感性和厌恶倾向都可以独特地预测污染恐惧。研究 2 中的增长曲线分析表明,即使在控制负性情绪的情况下,随着厌恶敏感性的增加,较高的基线污染恐惧与污染恐惧在 6 周内的减少程度较低有关。最后,在控制抑郁的情况下,在 OCD 患者中,研究 3 中的厌恶倾向与同时出现的过度洗涤症状有关。这些来自非临床、模拟和临床样本的发现,对未来研究 OCD 中与污染相关的易损性的特异性具有启示意义。