Bhikram Tracy, Abi-Jaoude Elia, Sandor Paul
From the Faculty of Medicine, University of Toronto (Bhikram, Abi-Jaoude, Sandor); the Tourette Syndrome Neurodevelopmental Clinic, Toronto Western Hospital (Bhikram, Abi-Jaoude, Sandor); the Department of Psychiatry, The Hospital for Sick Children (Abi-Jaoude); and the Division of Child Psychiatry, Department of Psychiatry, Youthdale Treatment Centres (Sandor), Toronto, Ont., Canada.
J Psychiatry Neurosci. 2017 Sep;42(5):300-306. doi: 10.1503/jpn.160079.
Recent research has identified the important role of disgust in the symptomatology of obsessive-compulsive disorder (OCD). Exaggerated and inappropriate disgust reactions may drive some of the symptoms of OCD, and in some cases, may even eclipse feelings of anxiety. This paper reviews behavioural and neuroimaging research that recognizes the prominent role of disgust in contributing to OCD symptoms, especially contamination-based symptoms. We discuss how elevated behavioural and biological markers of disgust reported in OCD populations support the need for alternative clinical treatment strategies and theoretical models of OCD.
最近的研究已经确定了厌恶在强迫症（OCD）症状学中的重要作用。过度且不适当的厌恶反应可能会引发强迫症的一些症状，在某些情况下，甚至可能掩盖焦虑情绪。本文回顾了行为学和神经影像学研究，这些研究认识到厌恶在导致强迫症症状，尤其是基于污染的症状方面所起的突出作用。我们讨论了强迫症患者群体中报告的厌恶行为和生物学指标升高如何支持对强迫症替代临床治疗策略和理论模型的需求。
