Mataran Pérez L, Rodríguez Pérez M, González Domínguez J, Gutiérrez Gea F, Abellán Pérez M, Salvatierra Ríos D
Servicio de Reumatología, Hospital Clínico Universitario de Granada.
An Med Interna. 1990 Mar;7(3):129-32.
The results of the comparison between phenotypic frequency of HLA antigen classes I and II in patients afflicted with rheumatoid arthritis (RA) and their relatives (study carried out in the east of Andalusian), showed a significant increase of HLA A24, B51, B44, CW1 ans CW5 class I antigen in the group of relatives. We found a statistically significant DR4 antigen class II increase in both, patients and relative groups. The marriage parther of patients with RA did not have variations in class I or II HLA antigens compared to the control group. We concluded that RA is probably related to the following antigens: A24, B51, B44, CW1, CW5 and DR4.
对患有类风湿性关节炎（RA）的患者及其亲属（在安达卢西亚东部开展的研究）的I类和II类HLA抗原表型频率进行比较的结果显示，亲属组中I类抗原HLA A24、B51、B44、CW1和CW5显著增加。我们发现，患者组和亲属组中II类抗原DR4在统计学上均显著增加。与对照组相比，RA患者的婚姻伴侣在I类或II类HLA抗原方面没有差异。我们得出结论，RA可能与以下抗原相关：A24、B51、B44、CW1、CW5和DR4。
