Kessel David
Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
J Porphyr Phthalocyanines. 2008 Jul 24;12(8):877-880. doi: 10.1142/s1088424608000273.
While the concept of photodynamic therapy dates from 1900, and there have been periodic re-discoveries, the clinical era really began with the studies by Dougherty and associates in the early 1970s. This report relates my encounter with the field of PDT, along with experimental approaches to the elucidation of pertinent phototoxic mechanisms.
虽然光动力疗法的概念可追溯到1900年,且时有重新发现,但临床时代真正始于20世纪70年代初多尔蒂及其同事的研究。本报告讲述了我在光动力疗法领域的经历,以及阐明相关光毒性机制的实验方法。