Department of Pediatric Cardiology and General Pediatrics, Medical University of Warsaw, 24 Marszalkowska St, 00-576, Warsaw, Poland.
Qual Life Res. 2011 May;20(4):537-41. doi: 10.1007/s11136-010-9780-8. Epub 2010 Oct 31.
The aim of our prospective study was to assess the health-related quality of life (HRQOL) of children with mitral valve prolapse (MVP) and the impact of clinical symptoms on HRQOL.
Sixty-seven patients with primary MVP aged 8-18 years were studied and compared with 31 healthy children. All children completed the polish version of KIDSCREEN-27. For searching occurrence and frequency of 18 clinical symptoms, authors' questionnaire was used.
The statistically significant difference was found only for one from five searching dimensions of HRQOL-physical well-being. In the remaining studied aspects of HRQOL, no statistically significant differences were found in comparison with the healthy children. The statistically significant moderate correlation between the number and frequency of clinical symptoms and physical well-being was found.
In children with MVP, the lower self-assessment is observed mainly in evaluation of their health and own physical activity. The remaining studied dimensions of HRQOL are comparable with the healthy children. However, within the population of children suffering from MVP, the frequency of clinical symptoms impact upon the different HRQOL dimensions. Thus, MVP represents a heterogeneous population. Whether there are impairments of HRQOL largely depend on the severity and frequency of clinical symptoms.
本前瞻性研究旨在评估二尖瓣脱垂(MVP)患儿的健康相关生活质量(HRQOL)以及临床症状对 HRQOL 的影响。
研究纳入 67 名年龄 8-18 岁的原发性 MVP 患儿,并与 31 名健康儿童进行比较。所有儿童均完成了波兰版 KIDSCREEN-27 量表的评估。为了寻找 18 种临床症状的发生和频率,作者使用了调查问卷。
仅在 HRQOL 的五个搜索维度之一——身体幸福感方面发现了统计学上的显著差异。在与健康儿童比较的其余 HRQOL 方面,未发现统计学上的显著差异。在身体幸福感方面,临床症状的数量和频率与身体幸福感之间存在统计学上的中度相关性。
在 MVP 患儿中,主要观察到他们对自身健康和身体活动的评估较低。其余研究的 HRQOL 维度与健康儿童相当。然而,在 MVP 患儿群体中,临床症状的频率会影响不同的 HRQOL 维度。因此,MVP 代表了一个异质的群体。HRQOL 是否受损在很大程度上取决于临床症状的严重程度和频率。