Suter Valérie G A, Altermatt Hans Jörg, Sendi Pedram, Mettraux Gérald, Bornstein Michael M
Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern.
Schweiz Monatsschr Zahnmed. 2010;120(8):664-71.
The present pilot study evaluates the histopathological characteristics and suitability of CO2 and diode lasers for performing excisional biopsies in the buccal mucosa with special emphasis on the extent of the thermal damage zone created.
15 patients agreed to undergo surgical removal of their fibrous hyperplasias with a laser. These patients were randomly assigned to one diode or two CO2 laser groups. The CO2 laser was used in a continuous wave mode (cw) with a power of 5 W (Watts), and in a pulsed char-free mode (cf). Power settings for the diode laser were 5.12 W in a pulsed mode. The thermal damage zone of the three lasers and intraoperative and postoperative complications were assessed and compared.
The collateral thermal damage zone on the borders of the excisional biopsies was significantly smaller with the CO, laser for both settings tested compared to the diode laser regarding values in pm or histopathological index scores. The only intraoperative complication encountered was bleeding, which had to be controlled with electrocauterization. No postoperative complications occurred in any of the three groups.
The CO2 laser seems to be appropriate for excisional biopsies of benign oral mucosal lesions. The CO2 laser offers clear advantages in terms of smaller thermal damage zones over the diode laser. More study participants are needed to demonstrate potential differences between the two different CO2 laser settings tested.
本初步研究评估二氧化碳激光和二极管激光在颊黏膜进行切除活检的组织病理学特征及适用性，特别强调所产生的热损伤区范围。
15名患者同意接受激光手术切除其纤维性增生组织。这些患者被随机分为一个二极管激光组或两个二氧化碳激光组。二氧化碳激光以5瓦的连续波模式（cw）以及无炭化脉冲模式（cf）使用。二极管激光在脉冲模式下的功率设置为5.12瓦。对三种激光的热损伤区以及术中、术后并发症进行评估和比较。
就微米值或组织病理学指数评分而言，在测试的两种设置下，与二极管激光相比，二氧化碳激光在切除活检边缘的旁侧热损伤区明显更小。唯一遇到的术中并发症是出血，需用电灼法控制。三组中均未发生术后并发症。
二氧化碳激光似乎适用于良性口腔黏膜病变的切除活检。与二极管激光相比，二氧化碳激光在热损伤区较小方面具有明显优势。需要更多的研究参与者来证明所测试的两种不同二氧化碳激光设置之间的潜在差异。
