Parajuly Shyam S, Lan Peng Yu, Yan Luo, Gang Yang Zhi, Lin Lan
Department of Diagnostic Ultrasound and The National Key Discipline of Medical Imaging and Nuclear Medicine, West China Hospital of Sichuan University, China.
Asian Pac J Cancer Prev. 2010;11(3):809-14.
The performance of ultrasound elastography in the characterization of 170 breast lesions with histologic correlation was evaluated in 150 consecutive patients who were diagnosed as having benign or malignant masses on B mode sonography. Each lesion was classified with ACR's BI-RADS lexicon (benign=2 and 3, malignant 4 and 5) using Ueno elastography classification scores (benign=1-3, malignant=4-5). Of the 170 lesions, 70 were histologically malignant, and 100 were benign. Ultrasound elastography was superior in detecting breast cancer, since the accuracy (95.8%), sensitivity (98.6%), specificity (96.0%), and positive predictive values (94.5%) were higher than those of B mode sonography (90.6%, 91.4%, 90.0% and 86.5% respectively). The sensitivity (98.57%) and false discovery rate (1.1%), when both modalities were jointly used (sonography and /UE) was better then those of sonography and UE singly. However, the specificity (90%) was found similar to sonography. In conclusion, ultrasound elastography is superior to B mode sonography in assessing the nature of breast lesions.
在150例经B超诊断为良性或恶性肿块的连续患者中，评估了超声弹性成像对170个乳腺病变进行组织学相关性特征分析的性能。使用上野弹性成像分类评分（良性=1 - 3，恶性=4 - 5），根据美国放射学会（ACR）的乳腺影像报告和数据系统（BI-RADS）词典对每个病变进行分类（良性=2和3，恶性=4和5）。170个病变中，70个组织学为恶性，100个为良性。超声弹性成像在检测乳腺癌方面更具优势，因为其准确性（95.8%）、敏感性（98.6%）、特异性（96.0%）和阳性预测值（94.5%）均高于B超（分别为90.6%、91.4%、90.0%和86.5%）。当联合使用两种检查方法（超声检查和超声弹性成像）时，敏感性（98.57%）和假发现率（1.1%）优于单独使用超声检查和超声弹性成像。然而，特异性（90%）与超声检查相似。总之，在评估乳腺病变的性质方面，超声弹性成像优于B超。
