Tardivon A, El Khoury C, Thibault F, Wyler A, Barreau B, Neuenschwander S
Service de Radiologie, Institut Curie, 26 rue d'Ulm, 75248 Paris cedex 05.
J Radiol. 2007 May;88(5 Pt 1):657-62. doi: 10.1016/s0221-0363(07)89872-6.
To evaluate elastography in the characterization of breast nodules.
Elastography (Hitachi, 7.5- to 13-MHz probe; Ueno classification, scores 1-3=benign, 4-5=malignant) was evaluated in 125 subclinical lesions in 114 patients. The results were compared to those of the ACR's BI-RADS sonography categories (benign=2 and 3, malignant=4 and 5) and to the results of the percutaneous samples taken and/or surgery (122 lesions evaluated, 59%<10 mm, 61 cancers, 61 benign lesions).
There were three technical failures (2.4%). The elastography was in agreement with histology for 101 lesions, with 13 false-negative results and eight false-positive results (sensitivity, 78.7%; specificity, 86.9%; PPV, 85.7%; NPV, 80.3%); versus agreement with the BI-RADS classification for 98 lesions with one false-negative result and 23 false-positive results (sensitivity, 98.4%; specificity, 47.5%; PPV, 65.2%; NPV, 96.7%).
Elastography is a simple and rapid complementary method that can improve the specificity and the PPV of morphological imaging studies of breast nodules with a low level of suspicion (BI-RADS categories 3 and 4a), which should decrease the rate of unnecessary benign biopsies.
评估弹性成像在乳腺结节特征描述中的作用。
对114例患者的125个亚临床病变进行弹性成像检查(日立,7.5 - 13兆赫兹探头;上野分类,评分1 - 3 =良性,4 - 5 =恶性)。将结果与美国放射学会(ACR)乳腺影像报告和数据系统(BI-RADS)超声分类结果(良性=2和3,恶性=4和5)以及经皮取样和/或手术结果(评估122个病变,59%<10毫米,61个癌症,61个良性病变)进行比较。
有3例技术失败(2.4%)。弹性成像与组织学结果在101个病变上一致,有13例假阴性结果和8例假阳性结果(敏感性,78.7%;特异性,86.9%;阳性预测值,85.7%;阴性预测值,80.3%);与BI-RADS分类在98个病变上一致,有1例假阴性结果和23例假阳性结果(敏感性,98.4%;特异性,47.5%;阳性预测值,65.2%;阴性预测值