招募和保留急诊医学临床试验中的患者。
Recruitment and retention of patients into emergency medicine clinical trials.
机构信息
Department of Biostatistics, The University of Alabama at Birmingham, USA.
出版信息
Acad Emerg Med. 2010 Oct;17(10):1104-12. doi: 10.1111/j.1553-2712.2010.00866.x.
Abstract
The emergency medicine (EM) and prehospital environments are unlike any other clinical environments and require special consideration to allow the successful implementation of clinical trials. This article reviews the specific issues involved in EM clinical trials and provides strategies from EM and non-EM trials to maximize recruitment and retention. While the evidence supporting some of these strategies is deficient, addressing recruitment and retention issues with specific strategies will help researchers deal with these issues in their funding applications and in turn develop the necessary infrastructure to participate in EM clinical trials.
摘要
急诊医学（EM）和院前环境与任何其他临床环境都不同，需要特别考虑，以允许临床试验的成功实施。本文回顾了 EM 临床试验中涉及的具体问题，并提供了来自 EM 和非 EM 试验的策略，以最大程度地招募和保留参与者。虽然这些策略中的一些证据不足，但通过具体策略解决招募和保留问题将有助于研究人员在其资助申请中处理这些问题，并最终发展必要的基础设施来参与 EM 临床试验。
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