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[苯扎贝特治疗血脂异常患者的血液粘度和红细胞变形能力变化]

[Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].

作者信息

Labiós Gómez M, Romero Simo M, Gabriel Botella F, Martín Valles H, Morera Llorca M, Freixas Ventura J

机构信息

Servicio de Medicina Interna, Hospital Clínico Universitario, Facultad de Medicina, Valencia.

出版信息

An Med Interna. 1990 Oct;7(10):517-21.

PMID:2104097
Abstract

31 patients afflicted with primary hyperlipidemia who did not improve after 30 days on a diet were treated with 1800 mg/day of binifibrate. We measured the total cholesterol level and triglyceridemia, as well as blood viscosity and red cell deformability at day 0, 30, 60, 90 of treatment. We found a statistically significant decrease in cholesterol and triglyceride levels as well as blood viscosity, and an increment of red cell deformability which improved the circulatory dynamisms augmentin the tissular perfusion in these patients.

摘要

31例原发性高脂血症患者在饮食控制30天后病情无改善,接受了每日1800毫克苯扎贝特的治疗。我们在治疗的第0、30、60、90天测量了总胆固醇水平、甘油三酯血症、血液粘度和红细胞变形性。我们发现胆固醇和甘油三酯水平以及血液粘度有统计学意义的下降,红细胞变形性增加,这改善了这些患者的循环动力并增强了组织灌注。

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