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[高脂血症患者的血液、血浆、红细胞黏度及红细胞滤过指数]

[Blood, plasma, erythrocyte viscosity and index of erythrocyte filtration in subjects with hyperlipemia].

作者信息

Craveri A, Tornaghi G, Paganardi L, Lanfredini M, Citella C, Leonardi G

出版信息

Minerva Med. 1987 Jun 30;78(12):823-9.

PMID:3601130
Abstract

40 hyperlipidaemic patients (26 type II a and b, 14 type IV) and 50 healthy controls were studied. The patients were not suffering from any other pathology of note and were under no drug treatment. Blood viscosity at natural Ht and at Ht 45% and plasma viscosity were measured. Red blood cell viscosity and deformability was studied on washed red cells, poor in leucocytes and platelets and suspended in a saline phosphate buffer. The patients with hyperlipidaemia had blood viscosity higher than healthy people. Red blood cell and plasma viscosity were higher in subjects with hyperlipidaemia. There was no difference in the filtration index between the people under study. The increased blood viscosity found in people with hyperlipidaemia appears to be attributable to changes in both the plasma and the erythrocytes.

摘要

对40名高脂血症患者(26例II a型和b型,14例IV型)和50名健康对照者进行了研究。这些患者未患有任何其他值得注意的病理状况,且未接受药物治疗。测量了自然血细胞比容、45%血细胞比容时的血液粘度以及血浆粘度。在洗涤过的红细胞上研究了红细胞粘度和变形性,这些红细胞白细胞和血小板含量低,并悬浮于磷酸盐缓冲盐溶液中。高脂血症患者的血液粘度高于健康人。高脂血症患者的红细胞和血浆粘度更高。研究对象之间的滤过指数没有差异。高脂血症患者中发现的血液粘度增加似乎归因于血浆和红细胞的变化。

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