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[某健康中心4年期间孕妇乙肝表面抗原研究的结果与分析]

[Results and analysis of research on HBsAg in pregnant women at a health center over 4 years].

作者信息

Delgado Sánchez A, Bailón Muñoz E, Sánchez Pérez M R, Tara Arriola J, Sánchez Mariscal M D, Vázquez Molina R

机构信息

Unidad Docente Provincial de Medicina Familiar y Comunitaria, Centro de Salud de Cartuja, Granada.

出版信息

Aten Primaria. 1990 Sep;7(8):556-60.

PMID:2104153
Abstract

Vertical transmission of hepatitis B is the primary means of acquiring the disease by new carriers. The Cartuja Health Center performs systemic screening of pregnant women subjects as possible carriers. The purpose of the study is to determine the prevalence of pregnant carriers, seroepidemiological characteristics and intervention guidelines followed. We reviewed 454 pregnant women with serology performed between 1986 and 1989, including factors such as age, race, HBV serology, risk, and subsequent prevention. We calculated the prevalence of carriers. Moreover, we compared the proportion of Gypsy carriers versus non-carriers, and the prevalence of Gypsy versus Payos (non-Gypsy) carriers. Fourteen cases were AgBHs (+) (3.1%). There was no age difference between carriers and non-carriers. The proportion of Gypsy women in the carrier group was higher than in the non-carrier group (p less than 0.01), while the prevalence of carriers was also higher in Gypsy women than in pregnant women of Payo origin (p = 0.00082). Only one carrier had prior risk history. Of the 14 women with AgBHs (+), 13 gave birth; the recommended guidelines were followed in 9 cases. Routine screening for AgBHs in pregnant women is justified by the low sensitivity of the risk criteria, and the possibility for prevention.

摘要

乙型肝炎的垂直传播是新携带者感染该疾病的主要途径。卡尔图亚健康中心对作为潜在携带者的孕妇进行系统筛查。本研究的目的是确定孕妇携带者的患病率、血清流行病学特征以及遵循的干预指南。我们回顾了1986年至1989年间进行血清学检查的454名孕妇,包括年龄、种族、乙肝病毒血清学、风险及后续预防等因素。我们计算了携带者的患病率。此外,我们比较了吉普赛携带者与非携带者的比例,以及吉普赛携带者与非吉普赛(帕约斯)携带者的患病率。14例为乙肝表面抗原阳性(3.1%)。携带者与非携带者之间在年龄上无差异。携带者组中吉普赛女性的比例高于非携带者组(p小于0.01),而吉普赛女性携带者的患病率也高于帕约斯族孕妇(p = 0.00082)。只有一名携带者有既往风险史。在14名乙肝表面抗原阳性的女性中,13名分娩;9例遵循了推荐指南。鉴于风险标准的低敏感性以及预防的可能性,对孕妇进行乙肝表面抗原的常规筛查是合理的。

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