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耶路撒冷孕妇中乙肝表面抗原携带者的患病率:向家庭成员水平传播的风险。

Prevalence of HBsAg carriers in pregnant women in Jerusalem: risk for horizontal transmission to family members.

作者信息

Isacsohn M, Halevy J, Eidelman A I, Rudensky B, Tadmor O P, Slater P E

机构信息

Infectious Disease Unit, Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Isr J Med Sci. 1994 May-Jun;30(5-6):368-70.

PMID:8034485
Abstract

A prospective study was undertaken in Jerusalem to quantitate the HBsAg prevalence rate in pregnant women, to assess the effect of ethnic origin on HBsAg prevalence rates, and to determine the impact of HBsAg carrier state on hepatitis B virus horizontal transmission in the family. Of the 6,572 women screened at the time of delivery, 42 (0.64%) were found to be HBsAg positive. Although the percentage of Moslem women was 3.4% of the total study population, they accounted for 23.8% of the HBsAg positive mothers. This resulted in a prevalence rate of 4.48% as compared to only 0.5% in the Jewish population (P < 0.01). Nine percent of siblings born to HBsAg positive mothers and 29% of the husbands were found to be horizontally infected.

摘要

在耶路撒冷进行了一项前瞻性研究,以量化孕妇中乙肝表面抗原(HBsAg)的流行率,评估种族起源对HBsAg流行率的影响,并确定HBsAg携带者状态对家庭中乙型肝炎病毒水平传播的影响。在分娩时接受筛查的6572名妇女中,有42名(0.64%)被发现HBsAg呈阳性。虽然穆斯林妇女占研究总人口的3.4%,但她们占HBsAg阳性母亲的23.8%。这导致流行率为4.48%,而犹太人群中仅为0.5%(P<0.01)。HBsAg阳性母亲所生的兄弟姐妹中有9%以及丈夫中有29%被发现受到水平感染。

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