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一组遭受性虐待儿童中的精神分裂症及其他精神障碍

Schizophrenia and other psychotic disorders in a cohort of sexually abused children.

作者信息

Cutajar Margaret C, Mullen Paul E, Ogloff James R P, Thomas Stuart D, Wells David L, Spataro Josie

机构信息

Centre for Forensic Behavioural Science, Monash University, Clifton Hill, Victoria, Australia.

出版信息

Arch Gen Psychiatry. 2010 Nov;67(11):1114-9. doi: 10.1001/archgenpsychiatry.2010.147.

Abstract

CONTEXT

The evidence for an association between child sexual abuse and subsequently developing psychotic disorders, including the schizophrenias, remains inconclusive.

OBJECTIVE

To explore whether child sexual abuse is a risk factor for later psychotic disorders.

DESIGN

Case-control study.

SETTING

Sample drawn from all notified cases of child sexual abuse over a 30-year period in Victoria, Australia.

PARTICIPANTS

A cohort of 2759 individuals ascertained as having been sexually abused when younger than 16 years had their subsequent contacts with mental health services established by data linkage. They were compared with a community-based control group matched on sex and age groupings whose rates of disorder were established using identical methods.

MAIN OUTCOME MEASURES

Rates of psychotic and schizophrenic illnesses.

RESULTS

Rates were significantly higher among child sexual abuse subjects compared with controls for psychosis in general (2.8% vs 1.4%; odds ratio, 2.1; 95% confidence interval, 1.4-3.1; P < .001) and schizophrenic disorders in particular (1.9% vs 0.7%; odds ratio, 2.6; 95% confidence interval, 1.6-4.4; P < .001). Those exposed to penetrative abuse had even higher rates of psychosis (3.4%) and schizophrenia (2.4%). Abuse without penetration was not associated with significant increases in psychosis or schizophrenia. The risks were highest for those whose abuse involved penetration, occurred after age 12 years, and involved more than 1 perpetrator, the combination producing rates of 8.6% for schizophrenia and 17.2% for psychosis.

CONCLUSIONS

Child sexual abuse involving penetration is a risk factor for developing psychotic and schizophrenic syndromes. The risk is greater for adolescents subjected to penetration. Irrespective of whether this statistical association reflects any causal link, it does identify an at-risk population in need of ongoing support and treatment.

摘要

背景

儿童性虐待与随后患上包括精神分裂症在内的精神障碍之间的关联证据尚无定论。

目的

探讨儿童性虐待是否为日后发生精神障碍的危险因素。

设计

病例对照研究。

设置

从澳大利亚维多利亚州30年间所有已通报的儿童性虐待病例中抽取样本。

参与者

一组2759名个体,经确定在16岁之前遭受过性虐待,通过数据链接确定他们随后与心理健康服务机构的接触情况。将他们与一个按性别和年龄组匹配的社区对照组进行比较,对照组的疾病发生率采用相同方法确定。

主要观察指标

精神疾病和精神分裂症的发病率。

结果

一般精神疾病方面,儿童性虐待受试者的发病率显著高于对照组(2.8%对1.4%;优势比,2.1;95%置信区间,1.4 - 3.1;P < 0.001),特别是精神分裂症(1.9%对0.7%;优势比,2.6;95%置信区间,1.6 - 4.4;P < 0.001)。遭受性侵犯的人精神疾病(3.4%)和精神分裂症(2.4%)的发病率更高。未发生性侵犯的虐待与精神疾病或精神分裂症的显著增加无关。对于那些性虐待涉及性侵犯、发生在12岁之后且涉及多名施虐者的人,风险最高,这种情况导致精神分裂症发病率为8.6%,精神疾病发病率为17.2%。

结论

涉及性侵犯的儿童性虐待是发生精神疾病和精神分裂症综合征的危险因素。遭受性侵犯的青少年风险更大。无论这种统计关联是否反映任何因果关系,它确实识别出了一个需要持续支持和治疗的高危人群。

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