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通过立体光刻技术对生物相容性和可生物降解聚合物进行3D结构化处理。

3D structuring of biocompatible and biodegradable polymers via stereolithography.

作者信息

Gill Andrew A, Claeyssens Frederik

机构信息

Department of Materials Science and Engineering, Kroto Research Institute, University of Sheffield, Sheffield, UK.

出版信息

Methods Mol Biol. 2011;695:309-21. doi: 10.1007/978-1-60761-984-0_19.

Abstract

The production of user-defined 3D microstructures from biocompatible and biodegradable materials via free-form fabrication is an important step to create off-the-shelf technologies to be used as tissue engineering scaffolds. One method of achieving this is the microstereolithography of block copolymers, allowing high resolution microstructuring of materials with tuneable physical properties. A versatile protocol for the production and photofunctionalisation of pre-polymers for microstereolithography is presented along with a discussion of the possible microstereolithography set-ups and previous work in the field.

摘要

通过自由成型制造由生物相容性和可生物降解材料生产用户定义的3D微结构是创建现成技术以用作组织工程支架的重要一步。实现这一目标的一种方法是嵌段共聚物的微立体光刻,它允许对具有可调物理性质的材料进行高分辨率微结构化。本文介绍了一种用于微立体光刻预聚物生产和光功能化的通用方案,并讨论了可能的微立体光刻设置以及该领域以前的工作。

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