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与生活在法国的 2 型糖尿病患者心理和行为功能相关的因素。

Factors associated with psychological and behavioral functioning in people with type 2 diabetes living in France.

机构信息

CIC-EC CIE Inserm, University hospital of Nancy, France.

出版信息

Health Qual Life Outcomes. 2010 Nov 2;8:124. doi: 10.1186/1477-7525-8-124.

Abstract

BACKGROUND

To identify demographic and clinical factors associated with psychological and behavioral functioning (PBF) in people with type 2 diabetes living in France.

METHODS

In March 2002, approximately 10,000 adults, who had been reimbursed for at least one hypoglycemic treatment or insulin dose during the last quarter of 2001, received a questionnaire about their health status and PBF (3,646 responders). For this analysis, the 3,090 persons with type 2 diabetes, aged 18-85 years old were selected.PBF was measured with the adapted version of the Diabetes Health Profile for people with type 2 diabetes. This permitted the calculation of three functional scores - psychological distress (PD), barriers to activity (BA), and disinhibited eating (DE) - from 0 (worst) to 100 (best).

RESULTS

Major negative associations were observed with PBF for microvascular complications (a difference of 6.7 in the BA score between persons with and without microvascular complications) and severe hypoglycemia (difference of 7.9 in the BA score), insulin treatment (-8.5 & -9.5 in the PD & BA scores respectively, as compared to treatment with oral hypoglycemic agents), non-adherence to treatment (-12.3 in the DE score for persons forgetting their weekly treatment), increasing weight (-8.5 & -9.7 in the PD & DE scores respectively, as compared to stable weight), at least one psychiatrist visit in 2001 (-8.9 in the DE score), and universal medical insurance coverage (-7.9 in the PD score) (due to low income).

CONCLUSION

Prevention and management of microvascular complications or adherence to treatment (modifiable factors) could be essential to preserving or improving PBF among people with type 2 diabetes. A specific approach to type 2 diabetes management may be required in groups with a low socioeconomic profile (particularly people with universal medical insurance coverage), or other non modifiable factors.

摘要

背景

目的在于确定与法国 2 型糖尿病患者的心理和行为功能(PBF)相关的人口统计学和临床因素。

方法

2002 年 3 月,大约有 10000 名成年人,在 2001 年最后一个季度接受过至少一次低血糖治疗或胰岛素剂量的报销,收到了一份关于他们的健康状况和 PBF 的问卷(3646 名应答者)。对于这项分析,选择了年龄在 18-85 岁之间的 3090 名 2 型糖尿病患者。使用适合 2 型糖尿病患者的糖尿病健康状况问卷,对 PBF 进行了测量。这允许从 0(最差)到 100(最好)计算三个功能得分-心理困扰(PD)、活动障碍(BA)和不受抑制的饮食(DE)。

结果

PBF 与微血管并发症(有微血管并发症和无微血管并发症的人在 BA 评分上的差异为 6.7)和严重低血糖(BA 评分上的差异为 7.9)显著负相关,胰岛素治疗(与口服降糖药物治疗相比,PD 和 BA 评分分别下降 8.5 和 9.5)、治疗不依从(每周忘记治疗的人 DE 评分下降 12.3)、体重增加(PD 和 DE 评分分别增加 8.5 和 9.7,与体重稳定相比)、2001 年至少一次看精神科医生(DE 评分下降 8.9)和全民医疗保险覆盖(PD 评分下降 7.9)(由于收入低)。

结论

预防和管理微血管并发症或坚持治疗(可改变的因素)对于 2 型糖尿病患者保持或改善 PBF 可能至关重要。对于社会经济状况较低的人群(特别是有全民医疗保险覆盖的人群)或其他不可改变的因素,可能需要一种特定的 2 型糖尿病管理方法。

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