Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands.
Arch Phys Med Rehabil. 2010 Nov;91(11):1705-11. doi: 10.1016/j.apmr.2010.08.004.
To evaluate the efficacy of the Nijmegen Falls Prevention Program (NFPP) for persons with osteoporosis and a fall history in a randomized controlled trial. Persons with osteoporosis are at risk for fall-related fractures because of decreased bone strength. A decrease in the number of falls therefore is expected to be particularly beneficial for these persons.
Randomized controlled trial.
Hospital.
Persons with osteoporosis and a fall history (N=96; mean ± SD age, 71.0±4.7y; 90 women).
After baseline assessment, participants were randomly assigned to the exercise (n=50; participated in the NFPP for persons with osteoporosis [5.5wk]) or control group (n=46; usual care).
Primary outcome measure was fall rate, measured by using monthly fall calendars for 1 year. Secondary outcomes were balance confidence (Activity-specific Balance Confidence Scale), quality of life (QOL; Quality of Life Questionnaire of the European Foundation for Osteoporosis), and activity level (LASA Physical Activity Questionnaire, pedometer), assessed posttreatment subsequent to the program and after 1 year of follow-up.
The fall rate in the exercise group was 39% lower than for the control group (.72 vs 1.18 falls/person-year; risk ratio, .61; 95% confidence interval, .40-.94). Balance confidence in the exercise group increased by 13.9% (P=.001). No group differences were observed in QOL and activity levels.
The NFPP for persons with osteoporosis was effective in decreasing the number of falls and improving balance confidence. Therefore, it is a valuable new tool to improve mobility and independence of persons with osteoporosis.
在一项随机对照试验中，评估尼美根防跌倒计划（NFPP）对骨质疏松症和有跌倒史的个体的疗效。骨质疏松症患者由于骨强度降低而有跌倒相关骨折的风险。因此，预计跌倒次数的减少对这些人特别有益。
随机对照试验。
医院。
骨质疏松症和有跌倒史的个体（N=96；平均±标准差年龄，71.0±4.7 岁；90 名女性）。
在基线评估后，参与者被随机分配到锻炼组（n=50；参加骨质疏松症患者的 NFPP[5.5 周]）或对照组（n=46；常规护理）。
主要观察指标是跌倒率，通过使用每月跌倒日历进行为期 1 年的测量。次要结局指标是平衡信心（特定活动平衡信心量表）、生活质量（欧洲骨质疏松症基金会生活质量问卷）和活动水平（LASA 体力活动问卷、计步器），在治疗后和 1 年随访后进行评估。
锻炼组的跌倒率比对照组低 39%（.72 次/人年比 1.18 次/人年；风险比，.61；95%置信区间，.40-.94）。锻炼组的平衡信心增加了 13.9%（P=.001）。在生活质量和活动水平方面，两组间没有差异。
NFPP 对骨质疏松症患者有效，可减少跌倒次数并提高平衡信心。因此，它是提高骨质疏松症患者活动能力和独立性的一种有价值的新工具。
