Vroling Bas, Sanders Marijn, Baakman Coos, Borrmann Annika, Verhoeven Stefan, Klomp Jan, Oliveira Laerte, de Vlieg Jacob, Vriend Gert
CMBI, NCMLS, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 26-28, 6525 GA Nijmegen, The Netherlands.
Nucleic Acids Res. 2011 Jan;39(Database issue):D309-19. doi: 10.1093/nar/gkq1009. Epub 2010 Nov 2.
The GPCRDB is a Molecular Class-Specific Information System (MCSIS) that collects, combines, validates and disseminates large amounts of heterogeneous data on G protein-coupled receptors (GPCRs). The GPCRDB contains experimental data on sequences, ligand-binding constants, mutations and oligomers, as well as many different types of computationally derived data such as multiple sequence alignments and homology models. The GPCRDB provides access to the data via a number of different access methods. It offers visualization and analysis tools, and a number of query systems. The data is updated automatically on a monthly basis. The GPCRDB can be found online at http://www.gpcr.org/7tm/.
GPCRDB是一个分子类别特定信息系统(MCSIS),它收集、整合、验证并传播关于G蛋白偶联受体(GPCR)的大量异构数据。GPCRDB包含有关序列、配体结合常数、突变和寡聚体的实验数据,以及许多不同类型的计算衍生数据,如多序列比对和同源性模型。GPCRDB通过多种不同的访问方法提供对数据的访问。它提供可视化和分析工具以及许多查询系统。数据每月自动更新。可在http://www.gpcr.org/7tm/在线找到GPCRDB。