Gryn J, Crilley P
Department of Neoplastic Diseases, Hahnemann University, Philadelphia, PA 19102.
Bone Marrow Transplant. 1990 Apr;5(4):279-80.
Chronic graft-versus-host disease (GVHD) of the skin is a common complication of allogeneic bone marrow transplantation. It can be resistant to common methods of systemic immunosuppression. We report successful treatment of a patient with progressive cutaneous GVHD that was resistant to cyclosporine and steroids after allogeneic marrow transplantation for acute myelogenous leukemia using topical tretinoin (Retin-A).
皮肤慢性移植物抗宿主病（GVHD）是同种异体骨髓移植的常见并发症。它可能对全身免疫抑制的常用方法耐药。我们报告了1例急性髓性白血病患者在接受同种异体骨髓移植后发生的对环孢素和类固醇耐药的进行性皮肤GVHD，采用外用维甲酸（维甲酸）治疗成功。
