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支气管热成形术治疗严重哮喘。

Bronchial thermoplasty for severe asthma.

机构信息

Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, Ontario, Canada.

出版信息

Curr Opin Pulm Med. 2011 Jan;17(1):34-8. doi: 10.1097/MCP.0b013e3283410ae4.

Abstract

PURPOSE OF REVIEW

the present article will address the potential for bronchial thermoplasty to be used in addition to conventional medications to help us treat our patients with severe asthma.

RECENT FINDINGS

two recently published studies report on the use of bronchial thermoplasty in patients with severe asthma. Now that patients with a range of asthma severity have been treated with bronchial thermoplasty, we are better able to comment on the appropriate selection of patients for this therapy that should optimize benefits and limit complications. In addition, studies reporting longer term follow-up are now available indicating the persistence of benefit and the absence of late developing adverse events.

SUMMARY

bronchial thermoplasty represents a novel approach to asthma treatment that is complementary to anti-inflammatory and bronchodilating therapies. Criteria for selecting appropriate patients are established and experience with bronchial thermoplasty is expanding since US Food and Drug Administration approval was obtained in April 2010.

摘要

目的综述

本文将探讨支气管热成形术除常规药物治疗以外的潜在应用,以帮助我们治疗严重哮喘患者。

最新发现

两项最近发表的研究报告了支气管热成形术在严重哮喘患者中的应用。现在,已经有一系列不同严重程度的哮喘患者接受了支气管热成形术治疗,因此我们能够更好地对这种治疗方法的患者选择进行评价,以便使治疗的获益最大化,并减少并发症。此外,目前也有更长时间随访的研究报告,表明该获益具有持续性,并且没有迟发性不良事件发生。

总结

支气管热成形术是一种治疗哮喘的新方法,与抗炎和支气管扩张治疗相辅相成。自 2010 年 4 月美国食品和药物管理局批准以来,选择合适患者的标准已经建立,并且支气管热成形术的应用经验也在不断扩展。

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