Division of Gastroenterological Surgery, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba, 260-0801, Japan.
Surg Today. 2010 Nov;40(11):1050-4. doi: 10.1007/s00595-009-4234-z. Epub 2010 Nov 3.
We conducted this randomized trial to compare the LigaSure Vessel Sealing System with conventional methods in gastrointestinal carcinoma surgery at five specialty cancer hospitals.
Patients with resectable stomach or colorectal cancers were randomized to the LigaSure (n = 100) or conventional surgery (n = 74) groups according to sealed envelopes. The operative data were compared.
There were no significant differences in operating times, blood loss, postoperative complications, or hospital stay. However, at the hospital where most of the procedures took place, the LigaSure was associated with a shorter operating time (173 ± 43 min for gastric carcinoma and 157 ± 43 min for colorectal carcinoma vs 211 ± 55 min and 202 ± 55 min for conventional surgery; P = 0.0046 and P = 0.0200, respectively) and less blood loss (300 ± 196 ml and 150 ± 133 ml, respectively, vs 453 ± 387 ml and 382 ± 444 ml; P = 0.0482 and P = 0.0465, respectively).
The LigaSure is safe for both gastric and colorectal cancer surgery with extended lymph node dissection. Used effectively, the device appears to reduce operating times and blood loss, although this requires confirmation in a larger series.
我们进行这项随机试验，旨在比较 LigaSure 血管结扎系统与 5 家肿瘤专科医院胃肠道癌手术中的传统方法。
根据密封信封，将可切除的胃癌或结直肠癌患者随机分为 LigaSure 组（n = 100）或传统手术组（n = 74）。比较手术数据。
手术时间、出血量、术后并发症和住院时间无显著差异。然而，在大多数手术进行的医院，LigaSure 与较短的手术时间相关（胃癌为 173 ± 43 min，结直肠癌为 157 ± 43 min，与传统手术相比分别为 211 ± 55 min 和 202 ± 55 min；P = 0.0046 和 P = 0.0200），出血量较少（胃癌为 300 ± 196 ml，结直肠癌为 150 ± 133 ml，与传统手术相比分别为 453 ± 387 ml 和 382 ± 444 ml；P = 0.0482 和 P = 0.0465）。
LigaSure 用于胃癌和结直肠癌的手术，包括扩大淋巴结清扫，是安全的。如果有效地使用该设备，似乎可以减少手术时间和出血量，但这需要在更大的系列中得到证实。
