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印度天然产物药物发现研究:现状与评估

Natural products drug discovery research in India: status and appraisal.

作者信息

Bhutani Kamlesh K, Gohil Vikrantsinh M

机构信息

Department of Natural Products, National Institute of Pharmaceutical Education and Research, Sector 67, SAS Nagar 160 062, India.

出版信息

Indian J Exp Biol. 2010 Mar;48(3):199-207.

Abstract

Discovery of a new drug is time consuming and laborious process. Natural products have long been a thriving source for the discovery of new drugs due to their chemical diversity and ability to act on various biological targets. The phytochemical exploration of indigeneous flora has contributed to some extent in this race for the discovery of new drugs. The traditional Indian systems of medicine has been a part of our lifestyle since ages and the classical texts like Ayurveda and Charak Samhita have served as materia medica for this purpose. This review focuses on the contributions made from India in the drug discovery and development process and provides future directions in the area.

摘要

发现一种新药是一个耗时费力的过程。由于天然产物具有化学多样性以及作用于各种生物靶点的能力,长期以来它们一直是发现新药的丰富来源。本土植物群的植物化学探索在这场新药发现竞赛中做出了一定贡献。传统的印度医学体系自古以来就是我们生活方式的一部分,像阿育吠陀和《阇罗迦本集》这样的经典文献一直充当着这方面的药物学著作。这篇综述聚焦于印度在药物发现与开发过程中所做的贡献,并提供了该领域的未来发展方向。

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