National Cancer Registry Programme (ICMR), M.S. Ramaiah Medical College, Bangalore, India.
Eur J Cancer Prev. 2011 Jan;20(1):25-32. doi: 10.1097/CEJ.0b013e3283410166.
Reports of increasing rates of cancer of the corpus uteri in several countries prompted this analysis of time trends. This study reports the trends in the incidence rate of cancer of the corpus uteri in Indian women. The data published in Cancer Incidence in Five Continents for various Indian registries for different periods and/or publication by the individual registries served as the source material. The mean annual percentage change in the incidence rates was computed using the relative difference between two time periods (latest and furthermost) and estimation of annual percentage change (EAPC) was also computed by the Poisson regression model. In 1998-2005, the incidence rate of cancer of the corpus uteri [age standardized rate (ASR)], was highest in Delhi and lowest in Pune and Imphal West (4.4 and 0.0 per 100,000 woman-years, respectively). The incidence rate in most of the registries between the two time periods showed an increase with few exceptions. Estimation of EAPC carried out in Mumbai, Chennai, and Bangalore PBCRs for the period 1983-2002 showed statistically significant increases in crude rate, ASR, and age-specific incidence rates (ASIR). The largest EAPC in ASR was in Bangalore (6.4%) and the smallest in Chennai (1.8%). Incidence trends for cancer of the corpus uteri appeared to result from an increase in the prevalence of risk factors and in improvement in diagnostic procedures. Most cancer of the corpus uteri is environmental in origin. Limiting fat consumption and avoiding excess energy intake may result in some reduction in the incidence of cancer of the corpus uteri.
一些国家报告称，子宫体癌的发病率不断上升，这促使人们对其时间趋势进行了分析。本研究报告了印度女性子宫体癌发病率的趋势。本研究使用了不同时期（最新和最久远）两个时间段之间的相对差异来计算发病率的年均百分比变化，并通过泊松回归模型计算了年度百分比变化（EAPC）的估计值。1998-2005 年，德里的子宫体癌发病率[年龄标准化率（ASR）]最高，而浦那和因帕尔西部最低（分别为每 10 万名妇女 4.4 和 0.0 例）。在这两个时间段之间，大多数登记处的发病率都有所上升，但也有少数例外。对孟买、钦奈和班加罗尔 PBCR 进行的 1983-2002 年期间 EAPC 的估计表明，粗率、ASR 和年龄特异性发病率（ASIR）均呈统计学显著上升。ASR 中 EAPC 最大的是班加罗尔（6.4%），最小的是钦奈（1.8%）。子宫体癌发病率的趋势似乎是由于危险因素的流行率增加和诊断程序的改善所致。大多数子宫体癌是由环境因素引起的。限制脂肪摄入和避免摄入过多的能量可能会导致子宫体癌的发病率有所降低。
