Oksuz Cigdem, Kilinc Muhammed, Yildirim Sibel A
Department of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey. Tel. +90 (312) 3052525. Fax: +90 (312) 3052012. E-mail:
Neurosciences (Riyadh). 2009 Oct;14(4):355-9.
To evaluate the health related quality of life (HRQoL) of totally independent ambulatory neuromuscular disease (NMD) patients in comparison with age matched healthy control subjects, and to assess associations between socio demographic variables and HRQoL in totally independent NMD patients.
Ninety-nine adult patients with a diagnosis of NMD referred to the Physical Therapy Department of the Health Sciences Faculty of Hacettepe University, Ankara, Turkey between 2007 and 2009 were included in the study. The Functional Independence Measurement and the Nottingham Health Profile (NHP) were the main outcomes to assess independence level in activities of daily living and quality of life.
The HRQoL score as measured by NHP was high (worse) in patients than healthy controls, and the difference between the 2 groups was significant for energy, physical mobility, and total score. Employed NMD patients scored significantly lower (better) than those unemployed in the majority of NHP domains. The genders and duration of illness displayed no significant difference in all dimension scores.
All NMD patients had a poorer HRQoL than with healthy subjects with respect to energy, physical mobility dimensions, and total score. Furthermore, occupation was found to be a main factor that affects HRQoL in adult ambulatory NMD patients.
评估完全独立行走的神经肌肉疾病（NMD）患者与年龄匹配的健康对照者相比的健康相关生活质量（HRQoL），并评估完全独立的NMD患者社会人口统计学变量与HRQoL之间的关联。
纳入2007年至2009年间转诊至土耳其安卡拉哈杰泰佩大学健康科学学院物理治疗科的99例诊断为NMD的成年患者。功能独立性测量和诺丁汉健康概况（NHP）是评估日常生活活动独立性水平和生活质量的主要指标。
NHP测量的患者HRQoL得分较高（较差），两组在精力、身体活动能力和总分方面的差异具有统计学意义。在大多数NHP领域，就业的NMD患者得分显著低于（更好）未就业患者。性别和病程在所有维度得分上均无显著差异。
在精力、身体活动能力维度和总分方面，所有NMD患者的HRQoL均比健康受试者差。此外，职业被发现是影响成年行走型NMD患者HRQoL的主要因素。
