Soares Cristiane N, Castro Mauro J Cabral, Peralta José M, Freitas Marcos R G de, Puccioni-Sohler Marzia
Neurology Service, Antônio Pedro Hospital, Fluminense Federal University, Brazil.
Arq Neuropsiquiatr. 2010 Oct;68(5):761-3. doi: 10.1590/s0004-282x2010000500016.
Meningitis and encephalitis are complications of West Nile virus (WNV) infection. Although WNV is endemic in North America, the virus has recently been reported in Colombia and Argentina. Investigation of WNV in Brazil is important since this virus has never been studied previously in this country.
To investigate the presence of WNV infection in viral encephalitis/meningitis cases of unknown etiology in the city of Rio de Janeiro, Brazil.
Thirty-seven adults with viral meningitis/encephalitis had their serum and CSF tested for WNV antibodies using the ELISA method.
Only one case was WNV-positive, but this case was also positive for dengue. The plaque reduction neutralization test distinguished infections, and was negative for WNV.
WNV can be confused with dengue infection. Their symptoms and neurological picture are similar. We did not find WNV in any patients with encephalitis and meningitis in the city of Rio de Janeiro. Up to now, it has not been detected in Brazil.
脑膜炎和脑炎是西尼罗河病毒（WNV）感染的并发症。尽管WNV在北美为地方性流行，但该病毒最近在哥伦比亚和阿根廷也有报道。对巴西的WNV进行调查很重要，因为此前该国从未对该病毒进行过研究。
调查巴西里约热内卢市病因不明的病毒性脑炎/脑膜炎病例中WNV感染的情况。
对37例病毒性脑膜炎/脑炎成年患者的血清和脑脊液采用酶联免疫吸附测定（ELISA）法检测WNV抗体。
仅1例WNV呈阳性，但该病例登革热检测也呈阳性。蚀斑减少中和试验可区分感染情况，该病例WNV检测为阴性。
WNV感染可能与登革热感染相混淆。它们的症状和神经症状相似。在里约热内卢市，我们未在任何脑炎和脑膜炎患者中发现WNV。截至目前，巴西尚未检测到该病毒。
