Tedebark Ulf, Scozzari Anthony, Werbitzky Oleg, Capaldi Daniel, Holmberg Lars
GE Healthcare Bio-Sciences, Uppsala, Sweden.
Methods Mol Biol. 2011;683:505-24. doi: 10.1007/978-1-60761-919-2_36.
This chapter describes the manufacturing process to a certain level for a possible oligonucleotide cargo and a peptide API in a multi-kilogram scale from a manufacture's point of view. In the concluding remarks, possible conjugation methods will be discussed from an industrial-scale perspective.
