Erasmus MC, University Medical Center Rotterdam, Dept, of Public Health, the Netherlands.
BMC Public Health. 2010 Nov 5;10:674. doi: 10.1186/1471-2458-10-674.
Chronic hepatitis B virus infection (HBV) is an important health problem in the Turkish community in the Netherlands, and promotion of screening for HBV in this risk group is necessary. An individually tailored intervention and a culturally tailored intervention have been developed to promote screening in first generation 16-40 year old Turkish immigrants. This paper describes the design of the randomized controlled trial, which will be used to evaluate the effectiveness of the two tailored internet interventions as compared to generic online information on HBV, and to assess the added value of tailoring on socio-cultural factors.
METHODS/DESIGN: A cluster randomized controlled trial design, in which we invite all Rotterdam registered inhabitants born in Turkey, aged 16-40 (n = 10,000), to visit the intervention website is used. A cluster includes all persons living at one house address. The clusters are randomly assigned to either group A, B or C. On the website, persons eligible for testing will be selected through a series of exclusion questions and will then continue in the randomly assigned intervention group. Group A will receive generic information on HBV. Group B will receive individually tailored information related to social-cognitive determinants of screening. Group C will receive culturally tailored information which, next to social-cognitive factors, addresses cultural factors related to screening. Subsequently, participants may obtain a laboratory form, with which they can be tested free of charge at local health centres. The main outcome of the study is the percentage of eligible persons tested for HBV through to participation in one of the three groups. Measurements of the outcome behaviour and its determinants will be at baseline and five weeks post-intervention.
This trial will provide information on the effectiveness of a culturally tailored internet intervention promoting HBV-screening in first generation Turkish immigrants in the Netherlands, aged 16-40. The results will contribute to the evidence base for culturally tailored (internet) interventions in ethnic minority populations. An effective intervention will lead to a reduction of the morbidity and mortality due to HBV in this population. This may not only benefit patients, but also help reduce health inequalities in western countries.
The Netherlands National Trial Register NTR 2394.
慢性乙型肝炎病毒感染(HBV)是荷兰土耳其裔社区的一个重要健康问题,有必要在该高危人群中推广 HBV 筛查。已经制定了个性化干预措施和文化适应性干预措施,以促进第一代 16-40 岁土耳其移民进行筛查。本文描述了一项随机对照试验的设计,该试验将用于评估两种个性化互联网干预措施与 HBV 通用在线信息相比的有效性,并评估社会文化因素个性化的附加价值。
方法/设计:采用整群随机对照试验设计,邀请所有在鹿特丹注册、出生于土耳其、年龄在 16-40 岁之间的居民(n=10000 人)访问干预网站。一个集群包括所有居住在一个地址的人。集群被随机分配到 A、B 或 C 组。在网站上,通过一系列排除问题筛选出有资格进行检测的人,然后继续随机分配到干预组。A 组将获得 HBV 的通用信息。B 组将获得与筛查的社会认知决定因素相关的个性化信息。C 组将获得文化适应性信息,除了社会认知因素外,还涉及与筛查相关的文化因素。随后,参与者可以获得一份实验室表格,凭此表格可以在当地卫生中心免费进行检测。研究的主要结果是通过参加三组中的一组接受 HBV 检测的合格人数百分比。在基线和干预后五周测量结局行为及其决定因素。
这项试验将提供关于个性化互联网干预措施在荷兰第一代 16-40 岁土耳其移民中促进 HBV 筛查的有效性信息。研究结果将为少数民族群体的文化适应性(互联网)干预措施提供证据基础。有效的干预措施将降低该人群因 HBV 引起的发病率和死亡率。这不仅有益于患者,还有助于减少西方国家的健康不平等。
荷兰国家试验注册中心 NTR 2394。