Department of Psychology, University of Iowa, Iowa City, IA, USA.
Psychol Med. 2011 Jul;41(7):1437-47. doi: 10.1017/S0033291710002096. Epub 2010 Nov 8.
The anxiety disorders are robust correlates/predictors of suicidal ideation, but it is unclear whether (a) the anxiety disorders are specifically associated with suicidal ideation or (b) the association is due to co-morbidity with depression and other disorders. One means of modeling co-morbidity is through the personality traits neuroticism/negative emotionality (N/NE) and extraversion/positive emotionality (E/PE), which account for substantial shared variance among the internalizing disorders. The current study examines the association between the internalizing disorders and suicidal ideation, after controlling for co-morbidity via N/NE and E/PE.
The sample consisted of 327 psychiatric out-patients. Multiple self-report and interview measures were collected for internalizing disorders [depression, generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), social anxiety, panic and specific phobia] and suicidal ideation, as well as self-report measures for N/NE and E/PE. A model was hypothesized in which each disorder and suicidal ideation was regressed on N/NE, and depression and social anxiety were regressed on E/PE. Structural equation modeling (SEM) was used to examine the unique association of suicidality with each disorder, beyond shared variance with N/NE and E/PE.
The hypothesized model was an acceptable fit to the data. Although zero-order analyses indicated that suicidal ideation was moderately to strongly correlated with all of the disorders, only depression and PTSD remained significantly associated with suicidal ideation in the SEM analyses.
In a latent variable model that accounts for measurement error and a broad source of co-morbidity, only depression and PTSD were uniquely associated with suicidal ideation; panic, GAD, social anxiety and specific phobia were not.
焦虑障碍是自杀意念的有力相关因素/预测因子,但目前尚不清楚焦虑障碍是否(a)与自杀意念有特定关联,还是(b)这种关联是由于与抑郁和其他障碍的共病引起的。一种建模共病的方法是通过神经质/负性情绪(N/NE)和外向性/正性情绪(E/PE)这两个人格特质,它们可以解释内化障碍之间的大量共同变异。本研究通过 N/NE 和 E/PE 控制共病后,考察了内化障碍与自杀意念之间的关联。
样本由 327 名精神科门诊患者组成。收集了多种自我报告和访谈测量来评估内化障碍[抑郁、广泛性焦虑症(GAD)、创伤后应激障碍(PTSD)、社交焦虑症、恐慌症和特定恐惧症]和自杀意念,以及神经质/负性情绪和外向性/正性情绪的自我报告测量。假设了一个模型,其中每个障碍和自杀意念都回归到 N/NE,抑郁和社交焦虑回归到 E/PE。结构方程模型(SEM)用于检验每个障碍与自杀意念的独特关联,而不仅仅是与 N/NE 和 E/PE 的共同变异。
假设模型与数据拟合良好。尽管零阶分析表明自杀意念与所有障碍都呈中度至高度相关,但在 SEM 分析中,只有抑郁和 PTSD 与自杀意念仍显著相关。
在一个考虑测量误差和广泛共病来源的潜在变量模型中,只有抑郁和 PTSD 与自杀意念有独特关联;恐慌症、GAD、社交焦虑症和特定恐惧症则没有。