抗炎和抗风湿药物对大鼠炎症的影响。
The effect of anti-inflammatory and antirheumatic drugs on inflammation in the rat.
作者信息
Woodland J, Currey H L, Vernon-Roberts B
出版信息
Curr Med Res Opin. 1977;5(1):3-10. doi: 10.1185/03007997709108968.
PMID:21056
Abstract
The anti-inflammatory effects of flurbiprofen and a number of other antirheumatic agents were studied in the rat using a model of inflammation, which involved the subcutaneous implantation of polyurethane cubes impregnated with an irritant. Results of acute and chronic studies indicated that flurbiprofen was extremely effective in suppressing both fluid and cellular phases of inflammation and, in this model, was comparable in potency to prednisolone.
摘要
利用一种炎症模型在大鼠身上研究了氟比洛芬和其他一些抗风湿药物的抗炎作用，该模型包括皮下植入浸渍有刺激物的聚氨酯立方体。急性和慢性研究结果表明，氟比洛芬在抑制炎症的液体和细胞阶段方面极其有效，并且在该模型中，其效力与泼尼松龙相当。
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引用本文的文献
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Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.
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