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尼日利亚东南部埃努古的双相情感障碍:患者的人口统计学和诊断特征。

Bipolar disorder in Enugu, South East Nigeria: demographic and diagnostic characteristics of patients.

机构信息

Department of Psychological Medicine, University of Nigeria Teaching Hospital, Enugu 400001, Nigeria.

出版信息

Psychiatr Danub. 2010 Nov;22 Suppl 1:S152-7.

Abstract

BACKGROUND AND OBJECTIVES

bipolar disorder is a severe mental disorder that has been widely studied in developed countries. Very few studies of this disorder exist in developing countries. The objective of this study was to describe the demographic and diagnostic characteristics of bipolar patients in Enugu, South East Nigeria.

SUBJECTS AND METHOD

the design of the study was cross-sectional. The study was carried out in Federal Neuropsychiatric Hospital Enugu (FNPHE) and in a Private Psychiatrist's Office (PPO) in Enugu, South East Nigeria. 94 patients were recruited to take part in the study. 49 patients were included from the FNPHE and 45 patients from the PPO. The two groups of patients differed only in terms of mood at study entry. Patients were included in the study if they had been diagnosed bipolar, if they were attending the FNPHE as outpatients, inpatients or were receiving emergency treatment or if they were attending the PPO for follow-up and if they had given their consent to participate in the study. The patients responded to a structured questionnaire used to elicit demographic and diagnostic characteristics. This questionnaire was administered by one of the authors (EJ). Each patient was also interviewed with the Mini International Neuropsychiatric Interview (MINI) for Bipolar Disorder Studies version 5.0.0. This MINI assessment was done by (MO). All the data were collected in a specially prepared data collection form. The demographic factors reported on included gender, age, marital status, level of education and employment status. The reported diagnostic and illness characteristics included age at onset of illness, mood at study entry and mood at onset of illness. The data were analyzed using SPSS version 11.5. Frequencies were run on demographic characteristics while means and standard deviations were calculated for continuous variables. The study was approved by the Research Ethics Committee of the FNPHE.

RESULTS

the majority of the sample (68.1%) met the criteria for bipolar I disorder. The mean age of patients was 33.17 (SD = 11.87) years and mean duration of bipolar illness was 9.6 (SD = 8.9) years. Among the 94 patients, 58.8% were males. The mean age at onset of illness for the whole group was 22.9 (SD = 8.3) years.

CONCLUSION

the current report is probably the first on bipolar disorder in this part of Africa. It will serve as an impetus to conduct more research on the topic especially since some important findings are similar to what had been recorded from both developed and developing countries.

摘要

背景与目的

双相情感障碍是一种严重的精神障碍,在发达国家已有广泛研究。发展中国家对此障碍的研究非常少。本研究旨在描述尼日利亚东南部埃努古的双相情感障碍患者的人口统计学和诊断特征。

对象与方法

本研究设计为横断面研究。研究在联邦神经精神医院(FNPHE)和埃努古的一家私人精神病医生办公室(PPO)进行。共招募了 94 名患者参与研究。其中 49 名患者来自 FNPHE,45 名患者来自 PPO。两组患者仅在研究入组时的情绪状态上有所不同。如果患者被诊断为双相情感障碍、正在 FNPHE 接受门诊、住院或急诊治疗,或正在 PPO 接受随访且同意参与研究,则将其纳入研究。患者回答了一份用于收集人口统计学和诊断特征的结构化问卷。问卷由作者之一(EJ)进行管理。每位患者还接受了 5.0.0 版迷你国际神经精神病访谈(MINI)的双相情感障碍研究评估。该 MINI 评估由(MO)进行。所有数据均收集在专门准备的数据收集表中。报告的人口统计学因素包括性别、年龄、婚姻状况、教育程度和就业状况。报告的诊断和疾病特征包括发病年龄、研究入组时的情绪和发病时的情绪。使用 SPSS 版本 11.5 进行数据分析。对人口统计学特征进行了频率分析,对连续变量进行了均值和标准差计算。该研究获得了 FNPHE 研究伦理委员会的批准。

结果

样本的大多数(68.1%)符合双相 I 型障碍的标准。患者的平均年龄为 33.17(SD=11.87)岁,双相情感障碍的平均病程为 9.6(SD=8.9)年。在 94 名患者中,58.8%为男性。整个组的发病年龄平均值为 22.9(SD=8.3)岁。

结论

本报告可能是非洲这一地区首次关于双相情感障碍的报告。它将成为开展该主题更多研究的动力,特别是因为一些重要发现与发达国家和发展中国家的记录相似。

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