Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Environ Sci Technol. 2010 Dec 1;44(23):9049-54. doi: 10.1021/es102582x. Epub 2010 Nov 9.
A method for isomer profiling of perfluorinated compounds (PFCs) in water was developed and applied to quantitatively assess the contributions from electrochemical (ECF) and telomer manufacturing processes around source regions of North America, Asia, and Europe. With the exception of 3 sites in Japan, over 80% of total perfluorooctanoate (PFOA, C(7)F(15)COO(-)) was from ECF, with the balance attributable to strictly linear (presumably telomer) manufacturing source(s). Comparing PFOA isomer profiles in samples from China, with PFOA obtained from a local Chinese manufacturer, indicated <3% difference in overall branched isomer content; thus, exclusive contribution from local ECF production cannot be ruled out. In Tokyo Bay, ECF, linear-telomer, and isopropyl-telomer sources contributed to 33%, 53%, and 14% of total PFOA, respectively. Perfluorooctane sulfonate (PFOS, C(8)F(17)SO(3)(-)) isomer profiles were enriched in branched content (i.e., >50% branched) in the Mississippi River but in all other locations were similar or only slightly enriched in branched content relative to historical ECF PFOS. Isomer profiles of other PFCs are also reported. Overall, these data suggest that, with the exception of Tokyo Bay, ECF manufacturing has contributed to the bulk of contamination around these source regions, but other sources are significant, and remote sites should be monitored.
开发了一种用于水中全氟化合物（PFCs）异构体分析的方法，并将其应用于定量评估北美的北美、亚洲和欧洲各地区电化学（ECF）和链转移剂制造工艺的贡献。除了日本的 3 个地点外，超过 80%的全氟辛酸（PFOA，C（7）F（15）COO（-））来自 ECF，其余部分归因于严格线性（推测为链转移剂）制造源。比较来自中国的 PFOA 异构体谱图与当地中国制造商生产的 PFOA，表明总支化异构体含量差异 <3%；因此，不能排除来自当地 ECF 生产的唯一贡献。在东京湾，ECF、线性-链转移剂和异丙基-链转移剂来源分别占总 PFOA 的 33%、53%和 14%。全氟辛烷磺酸（PFOS，C（8）F（17）SO（3）（-））异构体谱图在密西西比河地区支化含量丰富（即>50%支化），而在其他所有地区，与历史 ECF PFOS 相比，支化含量相似或仅略有富集。还报告了其他 PFC 的异构体谱图。总体而言，这些数据表明，除了东京湾外，ECF 制造对这些源区周围的大部分污染有贡献，但其他来源也很重要，应监测偏远地区。
