Friedman A J
Fertility and Endocrine Unit, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
J Reprod Med. 1990 Feb;35(2):113-5.
Sextuplet pregnancy occurred after human menopausal gonadotropin ovulation induction, intrauterine insemination and human chorionic gonadotropin support in the luteal phase. The patient's peak serum estradiol concentration was 861 pg/mL, and ultrasound monitoring demonstrated only one follicle greater than 11 mm in diameter. The possibility of high-order multiple birth exists despite intensive monitoring efforts for this therapy.