Yentzer Brad A, Fleischer Alan B
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1071, USA.
J Drugs Dermatol. 2010 Nov;9(11):1402-6.
Rosacea is a chronic skin condition that requires lifelong treatment. Given the rise in antibiotic-resistant bacteria, many physicians are re-evaluating their use of antibiotics for long-term treatment of rosacea.
To examine trends in the treatment of rosacea and the comorbidities associated with this skin condition.
From 2002-2006, the National Ambulatory Medical Care Survey queried drug mentions at rosacea visits and coexisting diagnoses. Prescribing patterns of dermatologists were compared to other physicians' patterns.
Ten million physician visits had the diagnosis of rosacea; 74 percent were associated with co-morbidities. Metronidazole, tetracyclines, azelaic acid and sodium sulfacetamide were the top medications mentioned at rosacea visits. Prescriptions increased for azelaic acid and decreased for sodium sulfacetamide. Dermatologists decreased their prescribing of systemic medications.
Dermatologists are reducing their use of systemic antibiotics for rosacea and turning to therapies, such as azelaic acid, that do not have potential to induce bacterial resistance.
酒渣鼻是一种需要终身治疗的慢性皮肤疾病。鉴于抗生素耐药菌的增多,许多医生正在重新评估他们使用抗生素长期治疗酒渣鼻的情况。
研究酒渣鼻的治疗趋势以及与这种皮肤疾病相关的合并症。
2002年至2006年期间,国家门诊医疗护理调查询问了酒渣鼻就诊时提及的药物及并存诊断情况。将皮肤科医生的处方模式与其他医生的模式进行了比较。
有1000万次医生就诊诊断为酒渣鼻;74%与合并症有关。甲硝唑、四环素、壬二酸和磺胺醋酰钠是酒渣鼻就诊时提及最多的药物。壬二酸的处方量增加,磺胺醋酰钠的处方量减少。皮肤科医生减少了全身性药物的处方。
皮肤科医生正在减少使用全身性抗生素治疗酒渣鼻,并转向使用如壬二酸等不会引发细菌耐药性的疗法。