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与达卡疫情相关的经肠道传播的非甲非乙型肝炎:流行病学及对公共卫生的影响

Enterically transmitted non-A, non-B hepatitis associated with an outbreak in Dhaka: epidemiology and public health implications.

作者信息

Hlady W G, Islam M N, Wahab M A, Johnson S D, Waiz A, Krawczynski K Z

机构信息

Epidemiology Department, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.

出版信息

Trop Doct. 1990 Jan;20(1):15-7. doi: 10.1177/004947559002000105.

Abstract

Investigation of an outbreak of hepatitis in Dhaka implicated enterically transmitted non-A, non-B (ET-NANB) hepatitis as the etiologic agent. This observation was made by exclusion in 17 of 19 patients, and confirmed serologically in one randomly selected patient by a fluorescent antibody blocking assay specific for ET-NANB hepatitis. These findings reinforce earlier suspicions that ET-NANB may be an important cause of acute hepatitis in Bangladesh. The epidemiology of ET-NANB hepatitis is discussed, and public health recommendations are made.

摘要

对达卡一次肝炎暴发的调查表明,经肠道传播的非甲非乙型(ET-NANB)肝炎是病原体。这一观察结果是通过对19名患者中的17名进行排除诊断得出的,并通过针对ET-NANB肝炎的荧光抗体阻断试验在一名随机选择的患者中得到血清学证实。这些发现强化了早期的怀疑,即ET-NANB可能是孟加拉国急性肝炎的一个重要病因。本文讨论了ET-NANB肝炎的流行病学,并提出了公共卫生建议。

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