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1
Surgery for pressure ulcers improves general health and quality of life in patients with spinal cord injury.脊髓损伤患者压力性溃疡的手术治疗可改善其总体健康状况和生活质量。
J Spinal Cord Med. 2010;33(4):396-400. doi: 10.1080/10790268.2010.11689718.
2
Improvisations in classic and modified techniques of flap surgery to improve the success rate for pressure ulcer healing in patients with spinal cord injury.在经典和改良皮瓣手术技术中进行创新,以提高脊髓损伤患者压疮愈合的成功率。
Int Wound J. 2013 Aug;10(4):455-60. doi: 10.1111/j.1742-481X.2012.01004.x. Epub 2012 Jun 14.
3
Complications after pressure ulcer surgery - a study of 118 operations in spinal cord injured patients.压力性溃疡手术后的并发症 - 对 118 例脊髓损伤患者手术的研究。
J Plast Surg Hand Surg. 2020 Jun;54(3):145-150. doi: 10.1080/2000656X.2020.1720700. Epub 2020 Jan 31.
4
Impact of pressure ulcers on individuals living with a spinal cord injury.压疮对脊髓损伤患者的影响。
Arch Phys Med Rehabil. 2014 Dec;95(12):2312-9. doi: 10.1016/j.apmr.2014.08.003. Epub 2014 Aug 25.
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Surgical management of pressure ulcers during inpatient neurologic rehabilitation: outcomes for patients with spinal cord disease.住院神经康复期间压疮的手术治疗:脊髓疾病患者的治疗结果
J Spinal Cord Med. 2009;32(2):125-31. doi: 10.1080/10790268.2009.11760763.
6
Severe pressure ulcers requiring surgery impair the functional outcome after acute spinal cord injury.严重的压疮需要手术治疗,会影响急性脊髓损伤后的功能预后。
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Pressure sores and blood and serum dysmetabolism in spinal cord injury patients.脊髓损伤患者的压疮与血液及血清代谢紊乱
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Spinal cord injury in Italy: A multicenter retrospective study.意大利的脊髓损伤:一项多中心回顾性研究。
Arch Phys Med Rehabil. 2001 May;82(5):589-96. doi: 10.1053/apmr.2001.21948.
9
Nutritional blood parameters and nutritional risk screening in patients with spinal cord injury and deep pressure ulcer-a retrospective chart analysis.脊髓损伤伴深部压疮患者的营养血液参数和营养风险筛查——一项回顾性图表分析。
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A pilot study evaluating protein abundance in pressure ulcer fluid from people with and without spinal cord injury.一项评估有无脊髓损伤人群压疮液中蛋白质丰度的试点研究。
J Spinal Cord Med. 2015 Jul;38(4):456-67. doi: 10.1179/2045772314Y.0000000212. Epub 2014 Jun 26.

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Flap Survival after Reconstructive Surgery for Pressure Ulcers: A Cohort Study.压力性溃疡重建手术后皮瓣存活情况:一项队列研究
Plast Reconstr Surg Glob Open. 2023 Dec 14;11(12):e5451. doi: 10.1097/GOX.0000000000005451. eCollection 2023 Dec.
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Effectiveness of Secretome from Human Umbilical Cord Mesenchymal Stem Cells in Gel (10% SM-hUCMSC Gel) for Chronic Wounds (Diabetic and Trophic Ulcer) - Phase 2 Clinical Trial.凝胶中人类脐带间充质干细胞分泌组(10% SM-hUCMSC凝胶)用于慢性伤口(糖尿病性和营养性溃疡)的有效性——2期临床试验
J Multidiscip Healthc. 2023 Jun 23;16:1763-1777. doi: 10.2147/JMDH.S408162. eCollection 2023.
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Treatment of Stage 4 Pressure Injuries With Autologous Heterogenous Skin Construct: A Single-Center Retrospective Study.自体异种皮肤构建物治疗4期压疮:一项单中心回顾性研究。
Eplasty. 2023 May 3;23:e26. eCollection 2023.
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[Influence factors of poor efficacy after flap repair operation in patients with pressure ulcers].[压力性溃疡患者皮瓣修复术后疗效不佳的影响因素]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Dec 20;38(12):1156-1161. doi: 10.3760/cma.j.cn501225-20220228-00041.
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Multidisciplinary treatment protocol for ischiatic, sacral, trochanteric or other pressure injuries in people with spinal cord injury: a retrospective cohort study.脊髓损伤患者坐骨、骶骨、转子或其他部位压疮的多学科治疗方案:回顾性队列研究。
Spinal Cord. 2023 Mar;61(3):204-210. doi: 10.1038/s41393-022-00869-9. Epub 2022 Dec 23.
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A longitudinal analysis of resting energy expenditure and body composition in people with spinal cord injury undergoing surgical repair of pressure injuries: a pilot study.脊髓损伤患者压力性损伤手术修复期间静息能量消耗和身体成分的纵向分析:一项试点研究。
Eur J Clin Nutr. 2023 Mar;77(3):386-392. doi: 10.1038/s41430-022-01248-6. Epub 2022 Dec 7.
7
Pedicled Chimeric Perforator Flap Based on Inferior Gluteal Vessel Axis for the Reconstruction of Stage-Four Primary Ischial Pressure Sores-A New Design.基于臀下血管轴的带蒂嵌合穿支皮瓣用于四期原发性坐骨压力性溃疡的重建——一种新设计
Indian J Plast Surg. 2021 Apr;54(2):177-185. doi: 10.1055/s-0041-1729505. Epub 2021 Jul 5.
8
Access and engagement with places in the community, and the quality of life among people with spinal cord damage.脊髓损伤人群对社区场所的使用和参与,以及他们的生活质量。
J Spinal Cord Med. 2022 Jul;45(4):522-530. doi: 10.1080/10790268.2020.1860867. Epub 2021 Jan 19.
9
Use of a Total Leg Fillet Flap to Cover Multiple Pelvic Pressure Ulcers.使用全腿鱼际皮瓣覆盖多处骨盆压疮。
Plast Reconstr Surg Glob Open. 2019 Jan 7;7(1):e2084. doi: 10.1097/GOX.0000000000002084. eCollection 2019 Jan.
10
Proximal femoral resection and Tensor Fascia Lata flap for recalcitrant trochanteric pressure ulcers.股骨近端切除术及阔筋膜张肌皮瓣治疗顽固性转子压疮。
Spinal Cord Ser Cases. 2019 Feb 5;5:15. doi: 10.1038/s41394-019-0157-0. eCollection 2019.

本文引用的文献

1
Our experience in treatment of pressure ulcers by using local cutaneous flaps.我们使用局部皮瓣治疗压疮的经验。
Prilozi. 2008 Jul;29(1):199-210.
2
Quality of life of people with spinal cord injury in Northern India.印度北部脊髓损伤患者的生活质量。
Int J Rehabil Res. 2008 Sep;31(3):247-51. doi: 10.1097/MRR.0b013e3282fb7d25.
3
[Six treatment principles of the basle pressure sore concept].[基底压力性溃疡概念的六项治疗原则]
Handchir Mikrochir Plast Chir. 2007 Jun;39(3):206-14. doi: 10.1055/s-2007-965311.
4
[Complications after spinal cord injuries and their influence on the effectiveness of rehabilitation].脊髓损伤后的并发症及其对康复效果的影响
Medicina (Kaunas). 2006;42(11):877-80.
5
Enteral nutritional support in prevention and treatment of pressure ulcers: a systematic review and meta-analysis.肠内营养支持在压力性溃疡防治中的应用:一项系统评价与Meta分析
Ageing Res Rev. 2005 Aug;4(3):422-50. doi: 10.1016/j.arr.2005.03.005.
6
Pressure sores and blood and serum dysmetabolism in spinal cord injury patients.脊髓损伤患者的压疮与血液及血清代谢紊乱
Spinal Cord. 2004 Aug;42(8):473-6. doi: 10.1038/sj.sc.3101622.
7
Nutritional markers, acute phase reactants and tissue inhibitor of matrix metalloproteinase 1 in elderly patients with pressure sores.老年压疮患者的营养指标、急性期反应物及基质金属蛋白酶1组织抑制剂
Gerontology. 2002 Sep-Oct;48(5):298-301. doi: 10.1159/000065253.
8
Health-related quality of life and pressure ulceration assessment in patients treated in the community.社区治疗患者的健康相关生活质量及压疮评估
Wound Repair Regen. 2002 May-Jun;10(3):133-40. doi: 10.1046/j.1524-475x.2002.11002.x.
9
Living with a pressure ulcer: a descriptive study of patients' experiences.与压疮共存:一项关于患者经历的描述性研究。
Br J Community Nurs. 2002 Jun;7(6 Suppl):10, 12, 14, 16, 20, 22. doi: 10.12968/bjcn.2002.7.Sup4.12615.
10
The lived experience of having a pressure ulcer: a qualitative analysis.患有压疮的亲身经历:一项定性分析。
Adv Skin Wound Care. 2000 Sep-Oct;13(5):225-35.

脊髓损伤患者压力性溃疡的手术治疗可改善其总体健康状况和生活质量。

Surgery for pressure ulcers improves general health and quality of life in patients with spinal cord injury.

作者信息

Singh Roop, Singh Raghubir, Rohilla Rajesh K, Siwach Ramchander, Verma Vineet, Kaur Kiranpreet

机构信息

Department of Orthopaedic Surgery, Paraplegia and Rehabilitation, Pt. B.D. Sharma PGIMS, Haryana, India.

出版信息

J Spinal Cord Med. 2010;33(4):396-400. doi: 10.1080/10790268.2010.11689718.

DOI:10.1080/10790268.2010.11689718
PMID:21061899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2964028/
Abstract

STUDY DESIGN

Prospective clinical study.

BACKGROUND

Pressure ulcers interfere with the rehabilitation process in patients with spinal cord injury (SCI) and are a significant deterrent to participation in activities that contribute to independent, productive, and satisfying life.

OBJECTIVE

To evaluate the effect of surgery for pressure ulcers on general health and quality of life in patients with SCI.

SETTING

Tertiary care center in northern India.

METHODS

Various types of flap surgery were performed on 30 patients with SCI and 32 pressure ulcers (stages III and IV). Outcome was evaluated using general improvement in health (hemoglobin, serum proteins, and general well-being), patient satisfaction, and global quality of life scores (according to the visual analog scale).

RESULTS

At admission, the mean values of global quality of life, hemoglobin, serum albumin, and total serum proteins were 50.15 (range, 30-65), 8.75 g/dL (range, 6-12 g/dL), 3.12 g/dL (range, 2.9-4.3 g/dL), and 5.21 (range, 5-6.2 g/dL), respectively. At 6-month follow up, mean values of global quality of life score, hemoglobin, serum albumin, and total serum proteins were 87.36 (range, 44-96), 10.85 g/dL (range, 8.2-13.5 g/dL), 3.89 g/dL (range, 3.2-4.5 g/dL), and 6.43 g/dL (range, 5.85-6.70 g/dL), respectively. The overall rise in quality of life scores, hemoglobin, serum albumin, and total serum proteins was statistically significant. Most of the patients (76.7%) reported improvement in subjective well-being, and 83.3% were satisfied with the ultimate outcome of the surgery.

CONCLUSION

Results suggest that surgery for stages III and IV pressure ulcers offers the greatest benefit to the patients in terms of improvement in general health (anemia, hypoproteinemia, and general well-being) and quality of life.

摘要

研究设计

前瞻性临床研究。

背景

压疮会干扰脊髓损伤(SCI)患者的康复进程,并且是参与有助于实现独立、富有成效和满意生活的活动的重大阻碍。

目的

评估压疮手术对SCI患者总体健康状况和生活质量的影响。

地点

印度北部的三级护理中心。

方法

对30例患有SCI且有32处压疮(III期和IV期)的患者进行了各种类型的皮瓣手术。使用健康状况的总体改善情况(血红蛋白、血清蛋白和总体健康状况)、患者满意度以及生活质量总体评分(根据视觉模拟量表)来评估结果。

结果

入院时,生活质量总体评分、血红蛋白、血清白蛋白和血清总蛋白的平均值分别为50.15(范围30 - 65)、8.75 g/dL(范围6 - 12 g/dL), 3.12 g/dL(范围2.9 - 4.3 g/dL)和5.21(范围5 - 6.2 g/dL)。在6个月的随访中,生活质量评分、血红蛋白、血清白蛋白和血清总蛋白的平均值分别为87.36(范围44 - 96)、10.85 g/dL(范围8.2 - 13.5 g/dL)、3.89 g/dL(范围3.2 - 4.5 g/dL)和6.43 g/dL(范围5.85 - 6.70 g/dL)。生活质量评分、血红蛋白、血清白蛋白和血清总蛋白的总体升高具有统计学意义。大多数患者(76.7%)报告主观健康状况有所改善,83.3%的患者对手术的最终结果感到满意。

结论

结果表明,III期和IV期压疮手术在改善总体健康状况(贫血、低蛋白血症和总体健康状况)和生活质量方面为患者带来了最大益处。