Department of Urology, Erasmus Medical Centre, Rotterdam, The Netherlands.
Urol Oncol. 2010 Nov-Dec;28(6):663-7. doi: 10.1016/j.urolonc.2009.12.013.
Prostate cancer screening has become very prevalent in most countries around the world since the early 1990's. A national interview study in the United States has reported 75% and the Bureau of Statistics of The Netherlands between 25% and 40% of PSA-use in men above the age of 50. PSA-driven early detection has led to an increase of prostate cancer incidence in most countries, which, later on, at least in the United States, slightly decreased and reached a steady state but returned to levels of the prescreening period. The possibility of early detection of prostate cancer is attractive to clinicians and potential patients in spite of the fact that until recently concrete evidence that screening would influence prostate cancer mortality was lacking.
自 20 世纪 90 年代初以来，前列腺癌筛查在世界上大多数国家变得非常普遍。美国的一项全国性访谈研究报告称，75%的 50 岁以上男性使用 PSA，荷兰统计局报告称，25%至 40%的男性使用 PSA。PSA 驱动的早期检测导致大多数国家的前列腺癌发病率上升，在美国，这种发病率后来至少略有下降，达到稳定状态，但又回到了筛查前的水平。尽管直到最近还缺乏筛查会影响前列腺癌死亡率的具体证据，但早期发现前列腺癌的可能性对临床医生和潜在患者都具有吸引力。
