小鼠γ干扰素无法抑制刚地弓形虫在小鼠成纤维细胞中的生长。
Murine gamma interferon fails to inhibit Toxoplasma gondii growth in murine fibroblasts.
作者信息
Schwartzman J D, Gonias S L, Pfefferkorn E R
机构信息
Department of Pathology, University of Virginia School of Medicine, Charlottesville 22908.
出版信息
Infect Immun. 1990 Mar;58(3):833-4. doi: 10.1128/iai.58.3.833-834.1990.
Abstract
Although treatment of human macrophages or fibroblasts with human gamma interferon results in the inhibition of intracellular Toxoplasma gondii, murine gamma interferon stimulated only murine macrophages, not murine fibroblasts, to inhibit T. gondii. This species difference may be important in understanding the control of acute and chronic toxoplasmosis.
摘要
虽然用人γ干扰素处理人巨噬细胞或成纤维细胞会抑制细胞内的刚地弓形虫，但鼠γ干扰素仅刺激鼠巨噬细胞而非鼠成纤维细胞来抑制刚地弓形虫。这种物种差异可能对于理解急性和慢性弓形虫病的控制很重要。
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