Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
ACS Nano. 2010 Dec 28;4(12):7387-94. doi: 10.1021/nn1022582. Epub 2010 Nov 10.
The electronic properties of graphene can be modulated by charged lipid bilayer adsorbing on the surface. Biorecognition events which lead to changes in membrane integrity can be monitored electrically using an electrolyte-gated biomimetic membrane-graphene transistor. Here, we demonstrate that the bactericidal activity of antimicrobial peptides can be sensed electrically by graphene based on a complex interplay of biomolecular doping and ionic screening effect.
石墨烯的电子性质可以通过吸附在表面的带电脂质双层来调节。通过使用电解质门控仿生膜-石墨烯晶体管，可以电监测导致膜完整性变化的生物识别事件。在这里，我们证明了基于生物分子掺杂和离子屏蔽效应的复杂相互作用，抗菌肽的杀菌活性可以通过基于石墨烯的器件来进行电检测。
