Department of Human Health and Nutritional Sciences, College of Biological Science, University of Guelph, Ontario, Canada.
Breast Cancer Res. 2010;12(5):211. doi: 10.1186/bcr2646. Epub 2010 Oct 26.
Breast cancer is the most common cancer among women worldwide. Estimates suggest up to 35% of cases may be preventable through diet and lifestyle modification. Growing research on the role of fats in human health suggests that early exposure in life to specific fatty acids, when tissues are particularly sensitive to their environment, can have long-term health impacts. The present review examines the role of dietary fat in mammary gland development and breast cancer throughout the lifecycle. Overall, n-3 polyunsaturated fatty acids have promising cancer-preventive effects when introduced early in life, and warrant further research to elucidate the mechanisms of action.
乳腺癌是全球女性最常见的癌症。据估计，多达 35%的病例可以通过饮食和生活方式的改变来预防。越来越多的关于脂肪在人类健康中的作用的研究表明，在生命早期，当组织对环境特别敏感时，接触特定的脂肪酸可能会对长期健康产生影响。本综述检查了饮食脂肪在乳腺发育和整个生命周期中的乳腺癌中的作用。总的来说，n-3 多不饱和脂肪酸在生命早期引入时具有有希望的抗癌作用，值得进一步研究以阐明其作用机制。
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