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胆总管囊肿合并慢性胰腺炎:临床表现与治疗

Choledochal cyst with chronic pancreatitis: presentation and management.

作者信息

Saluja Sundeep Singh, Mishra Pramod Kumar, Nayeem Mohammed, Nag Hridya Hulas

机构信息

Department of Gastrointestinal Surgery, GB Pant Hospital, New Delhi, India.

出版信息

JOP. 2010 Nov 9;11(6):601-3.

PMID:21068494
Abstract

CONTEXT

Choledochal cysts are benign congenital cystic dilatations of the common bile duct. They are usually associated with pancreatobiliary malunion resulting in long-term complications, such as acute pancreatitis and bile duct cancer. However, the occurrence of chronic pancreatitis with a choledochal cyst is rarely reported.

CASE REPORTS

We report three cases of choledochal cysts associated with chronic pancreatitis with their presentation and management. The choledochal cysts were classified according to the Alonso-Lej classification with Todani modifications, based on radiographic and operative findings. Chronic pancreatitis was defined using Marseille criteria (1984). Two patients had a type I choledochal cyst and one had a type IV-A. All cases had chronic calcific pancreatitis with a grossly dilated main pancreatic duct. Abdominal pain was the most common presentation, present in all three patients while jaundice was seen in one patient. The laboratory parameters and MRI/MRCP helped to confirm the diagnosis. All patients underwent cyst excision with drainage and had an uneventful postoperative course. At a median follow-up of 9 months, two patients were asymptomatic and one patient, who developed duodenal obstruction, underwent gastrojejunostomy.

CONCLUSIONS

the association of a choledochal cyst with chronic pancreatitis may be etiologically related. Excision of the cyst with lateral pancreaticojejunostomy can be performed safely and is usually curative.

摘要

背景

胆总管囊肿是胆总管的先天性良性囊性扩张。它们通常与胰胆管汇合异常相关,可导致长期并发症,如急性胰腺炎和胆管癌。然而,胆总管囊肿合并慢性胰腺炎的情况鲜有报道。

病例报告

我们报告3例胆总管囊肿合并慢性胰腺炎的病例及其临床表现和治疗情况。根据影像学和手术结果,按照Alonso-Lej分类法并经Todani修正对胆总管囊肿进行分类。采用马赛标准(1984年)定义慢性胰腺炎。2例患者为I型胆总管囊肿,1例为IV-A型。所有病例均为慢性钙化性胰腺炎,主胰管明显扩张。腹痛是最常见的表现,3例患者均有腹痛,1例患者出现黄疸。实验室检查参数及磁共振成像/磁共振胰胆管造影有助于确诊。所有患者均接受囊肿切除及引流术,术后恢复顺利。中位随访9个月时,2例患者无症状,1例出现十二指肠梗阻的患者接受了胃空肠吻合术。

结论

胆总管囊肿与慢性胰腺炎的关联可能存在病因学联系。囊肿切除联合胰管空肠侧侧吻合术可安全实施,且通常可治愈。

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Choledochal cyst with chronic pancreatitis: presentation and management.胆总管囊肿合并慢性胰腺炎:临床表现与治疗
JOP. 2010 Nov 9;11(6):601-3.
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Choledochal cysts with chronic pancreatitis in adults: report of two cases with a review of the literature.成人胆总管囊肿合并慢性胰腺炎:两例报告并文献复习
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Pancreatic complications in pediatric choledochal cysts.小儿先天性胆总管囊肿的胰腺并发症。
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Type IV congenital choledochal cyst concurrent with acute pancreatitis: a case report.IV型先天性胆总管囊肿并发急性胰腺炎:一例报告
Hepatobiliary Pancreat Dis Int. 2005 May;4(2):311-2.
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[Congenital dilatation of the common bile duct (congenital choledochal cyst)].[先天性胆总管扩张症(先天性胆管囊肿)]
Srp Arh Celok Lek. 2001 May-Jun;129 Suppl 1:47-50.
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Spontaneous choledochal cyst perforation in pregnancy with co-existent chronic pancreatitis.妊娠合并慢性胰腺炎时胆总管囊肿自发性穿孔
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Choledochal cysts in adults.成人胆总管囊肿
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