Lattari E, Velasques B, Paes F, Cunha M, Budde H, Basile L, Cagy M, Piedade R, Machado S, Ribeiro P
Institute of Psychiatry of Federal University of Rio de Janeiro, Bazil.
Rev Neurol. 2010 Nov 16;51(10):610-23.
Understanding how the human motor control operates is an important issue to the neuroscience. One example is how the motor cortex controls muscle activity, which can be observed through corticomuscular coherence (CMC).
Our study aimed to verify the influence of certain factors related to the fine motor control of force tasks on CMC. Our issue is if would be possible the strength of the coupling between the central and muscular systems measured by changes in oscillatory activity of beta- and gamma-band being influenced by these factors as much healthy subjects as patients.
Beta-band CMC was especially important when executing sustaining accurate control tasks, which need more concentration and effort. However, we found that beta-band CMC was influenced by some factors. With regard to gamma-band CMC, apparently a complex and continuous dynamic integration of several mechanisms would be necessary to modulate gamma-band CMC, since it was not modulated by magnitude of force. Therefore, it seems these mechanisms would be required to an adequate and effective neural networks operation when a dynamic force output is required.
Beta- and gamma-band CMC could enrich our understanding of the dynamic changes of the motor system not only in health subjects but also in neurological patients. It may serve as a sensitive index for quantifying dynamical changes in fine motor control of force. It has the potential to become a useful tool to characterize the patterns of changes in central nervous system's activities for the purposes of basic research, especially in restoring of motor function.
了解人类运动控制如何运作是神经科学中的一个重要问题。一个例子是运动皮层如何控制肌肉活动，这可以通过皮质-肌肉相干性（CMC）来观察。
我们的研究旨在验证与精细运动控制中的力任务相关的某些因素对CMC的影响。我们的问题是，通过β和γ频段振荡活动变化测量的中枢与肌肉系统之间的耦合强度是否会受到这些因素的影响，无论是健康受试者还是患者。
在执行持续精确控制任务时，β频段CMC尤为重要，这类任务需要更多的注意力和努力。然而，我们发现β频段CMC会受到一些因素的影响。关于γ频段CMC，显然需要几种机制进行复杂且持续的动态整合来调节γ频段CMC，因为它不受力的大小调节。因此，当需要动态力输出时，似乎这些机制对于神经网络的充分有效运作是必需的。
β和γ频段CMC不仅可以丰富我们对健康受试者，也可以丰富我们对神经疾病患者运动系统动态变化的理解。它可能作为一个敏感指标来量化力的精细运动控制中的动态变化。它有潜力成为一个有用的工具，用于在基础研究中，特别是在运动功能恢复方面，表征中枢神经系统活动的变化模式。
