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严重军团菌肺炎患者出现嗜酸性粒细胞浸润作为左氧氟沙星相关并发症：一例报告

Eosinophilic infiltrate in a patient with severe Legionella pneumonia as a levofloxacin-related complication: a case report.

作者信息

Facciolongo Nicola, Menzella Francesco, Castagnetti Claudia, Cavazza Alberto, Piro Roberto, Carbonelli Cristiano, Zucchi Luigi

机构信息

Department of Pneumology, S, Maria Nuova Hospital, 42123 Reggio Emilia, Italy.

出版信息

J Med Case Rep. 2010 Nov 11;4:360. doi: 10.1186/1752-1947-4-360.

DOI:10.1186/1752-1947-4-360
PMID:21070648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2993722/
Abstract

INTRODUCTION

Legionella pneumonia can appear with different levels of severity and it can often present with complications such as acute respiratory distress syndrome.

CASE PRESENTATION

We report the case of a 44-year-old Caucasian man with Legionella pneumonia with successive development of severe acute respiratory distress syndrome. During his stay in intensive care the clinical and radiological situation of the previously observed acute respiratory distress syndrome unexpectedly worsened due to acute pulmonary eosinophilic infiltrate of iatrogenic origin.

CONCLUSION

Levofloxacin treatment caused the occurrence of acute eosinophilic infiltrate. Diagnosis was possible following bronchoscopic examination using bronchoaspirate and transbronchial biopsy.

摘要

引言

军团菌肺炎可表现出不同程度的严重程度，且常伴有诸如急性呼吸窘迫综合征等并发症。

病例报告

我们报告一例44岁白种男性患军团菌肺炎并相继发展为严重急性呼吸窘迫综合征的病例。在其重症监护期间，先前观察到的急性呼吸窘迫综合征的临床和放射学状况因医源性急性肺嗜酸性粒细胞浸润而意外恶化。

结论

左氧氟沙星治疗导致急性嗜酸性粒细胞浸润的发生。通过支气管灌洗和经支气管活检进行支气管镜检查后得以确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/94345dc270ab/1752-1947-4-360-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/ca6f844044b3/1752-1947-4-360-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/9fea9c01f09f/1752-1947-4-360-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/316e49bc8179/1752-1947-4-360-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/94345dc270ab/1752-1947-4-360-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/ca6f844044b3/1752-1947-4-360-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/9fea9c01f09f/1752-1947-4-360-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/316e49bc8179/1752-1947-4-360-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be7c/2993722/94345dc270ab/1752-1947-4-360-4.jpg

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