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家庭医生干预促进久坐个体进行体育锻炼对心血管风险的影响。

Effect on cardiovascular risk of an intervention by family physicians to promote physical exercise among sedentary individuals.

机构信息

Unidad de Investigación de Atención Primaria, Centro de Salud la Alamedilla, REDIAPP, Salamanca, España,

出版信息

Rev Esp Cardiol. 2010 Nov;63(11):1244-52. doi: 10.1016/s1885-5857(10)70249-8.

Abstract

INTRODUCTION AND OBJECTIVES

To evaluate the effect of a program promoting physical activity (PEPAF) implemented by family physicians on cardiovascular risk reduction.

METHODS

The cluster randomized clinical trial involved 56 family physicians randomly allocated to an intervention group (n=29) and a control group (n=27). Of the patients recruited, only those aged 30-74 years (1915 PEPAF and 1783 control) were included in the analysis. The intervention involved giving general advice about the benefits of physical activity to all patients and prescribed advice to a subgroup of patients (30%) who agreed to an additional consultation. Outcome measures included risk factors and cardiovascular risk assessed using the Framingham-D'Agostino scale.

RESULTS

A significant decrease from baseline in systolic and diastolic blood pressure and pulse pressure was observed after 12 months in both groups (control group: -2.93 mmHg, -1.81 mmHg and -1.15 mmHg, respectively; PEPAF group: -3.35 mmHg, -1.4 mmHg, and -1.94 mmHg, respectively). The high-density lipoprotein cholesterol level increased (control group: +1.73 mg/dl; PEPAF group: +2.67 mg/dl), while the atherogenic index decreased (by 0.12 and 0.16 in the two groups, respectively), all from baseline (P< .05). Cardiovascular risk decreased by 0.68 (95% confidence interval [CI], 0.13-1.25) in the control group and 0.79 (95%CI, 0.22-1.35) in the PEPAF group. There was no significant difference in the improvement at 12 months between the groups.

CONCLUSIONS

Patients' participation in the project was effective in improving control of risk factors and decreasing cardiovascular risk. No significant difference in outcome was observed between the control group and the group participating in the program promoting physical activity.

摘要

简介和目的

评估家庭医生实施的促进身体活动(PEPAF)计划对降低心血管风险的效果。

方法

这项聚类随机临床试验涉及 56 名家庭医生,他们被随机分配到干预组(n=29)和对照组(n=27)。在招募的患者中,仅将年龄在 30-74 岁之间的患者(1915 名 PEPAF 和 1783 名对照)纳入分析。干预措施包括向所有患者提供关于身体活动益处的一般建议,并向同意额外咨询的亚组患者(30%)提供处方建议。评估的结果包括使用弗雷明汉-达戈斯蒂诺量表评估的危险因素和心血管风险。

结果

两组患者在 12 个月后血压、舒张压和脉压均从基线水平显著下降(对照组:分别下降 2.93mmHg、1.81mmHg 和 1.15mmHg;PEPAF 组:分别下降 3.35mmHg、1.4mmHg 和 1.94mmHg)。高密度脂蛋白胆固醇水平升高(对照组:+1.73mg/dl;PEPAF 组:+2.67mg/dl),而致动脉粥样硬化指数降低(两组分别降低 0.12 和 0.16),均与基线相比(P<0.05)。对照组的心血管风险降低了 0.68(95%置信区间[CI],0.13-1.25),PEPAF 组降低了 0.79(95%CI,0.22-1.35)。两组患者在 12 个月时的改善情况无显著差异。

结论

患者参与该项目可有效改善危险因素控制,降低心血管风险。在对照组和参与促进身体活动计划的组之间,在结果方面未观察到显著差异。

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