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增加身体活动和心肺适能的生活方式干预与结构化干预的比较:一项随机试验。

Comparison of lifestyle and structured interventions to increase physical activity and cardiorespiratory fitness: a randomized trial.

作者信息

Dunn A L, Marcus B H, Kampert J B, Garcia M E, Kohl H W, Blair S N

机构信息

The Cooper Institute for Aerobics Research, Dallas, TX 75230, USA.

出版信息

JAMA. 1999 Jan 27;281(4):327-34. doi: 10.1001/jama.281.4.327.

Abstract

CONTEXT

Even though the strong association between physical inactivity and ill health is well documented, 60% of the population is inadequately active or completely inactive. Traditional methods of prescribing exercise have not proven effective for increasing and maintaining a program of regular physical activity.

OBJECTIVE

To compare the 24-month intervention effects of a lifestyle physical activity program with traditional structured exercise on improving physical activity, cardiorespiratory fitness, and cardiovascular disease risk factors.

DESIGN

Randomized clinical trial conducted from August 1, 1993, through July 31, 1997.

PARTICIPANTS

Sedentary men (n = 116) and women (n = 119) with self-reported physical activity of less than 36 and 34 kcal/kg per day, respectively.

INTERVENTIONS

Six months of intensive and 18 months of maintenance intervention on either a lifestyle physical activity or a traditional structured exercise program.

MAIN OUTCOME MEASURES

Primary outcomes were physical activity assessed by the 7-Day Physical Activity Recall and peak oxygen consumption (VO2peak) by a maximal exercise treadmill test. Secondary outcomes were plasma lipid and lipoprotein cholesterol concentrations, blood pressure, and body composition. All measures were obtained at baseline and at 6 and 24 months.

RESULTS

Both the lifestyle and structured activity groups had significant and comparable improvements in physical activity and cardiorespiratory fitness from baseline to 24 months. Adjusted mean changes (95% confidence intervals [CIs]) were 0.84 (95% CI, 0.42-1.25 kcal/kg per day; P<.001) and 0.69 (95% CI, 0.25-1.12 kcal/kg day; P = .002) for activity, and 0.77 (95% CI, 0.18-1.36 mL/kg per minute; P = .01) and 1.34 (95% CI, 0.72-1.96 mL/kg per minute; P<.001) for VO2peak for the lifestyle and structured activity groups, respectively. There were significant and comparable reductions in systolic blood pressure (-3.63 [95% CI, -5.54 to -1.72 mm Hg; P<.001] and -3.26 [95% CI, -5.26 to -1.25 mm Hg; P = .002]) and diastolic blood pressure (-5.38 [95% CI, -6.90 to -3.86 mm Hg; P<.001] and -5.14 [95% CI, -6.73 to -3.54 mm Hg; P<.001) for the lifestyle and structured activity groups, respectively. Neither group significantly changed their weight (-0.05 [95% CI, -1.05 to 0.96 kg; P = .93] and 0.69 [95% CI, -0.37 to 1.74 kg; P = .20]), but each group significantly reduced their percentage of body fat (-2.39% [95% CI, -2.92% to -1.85%; P<.001] and -1.85% [95% CI, -2.41 % to -1.28%; P<.001]) in the lifestyle and structured activity groups, respectively.

CONCLUSIONS

In previously sedentary healthy adults, a lifestyle physical activity intervention is as effective as a structured exercise program in improving physical activity, cardiorespiratory fitness, and blood pressure.

摘要

背景

尽管缺乏身体活动与健康状况不佳之间的密切关联已有充分记录,但60%的人口身体活动不足或完全不活动。传统的运动处方方法在增加和维持规律身体活动计划方面尚未被证明有效。

目的

比较生活方式身体活动计划与传统结构化运动对改善身体活动、心肺适能和心血管疾病危险因素的24个月干预效果。

设计

1993年8月1日至1997年7月31日进行的随机临床试验。

参与者

自我报告的身体活动分别少于每天36千卡/千克和34千卡/千克的久坐男性(n = 116)和女性(n = 119)。

干预措施

对生活方式身体活动或传统结构化运动计划进行6个月的强化干预和18个月的维持干预。

主要结局指标

主要结局是通过7天身体活动回忆评估的身体活动以及通过最大运动跑步机测试评估的峰值摄氧量(VO2peak)。次要结局是血浆脂质和脂蛋白胆固醇浓度、血压和身体成分。所有测量均在基线、6个月和24个月时进行。

结果

从基线到24个月,生活方式组和结构化活动组在身体活动和心肺适能方面均有显著且相当的改善。生活方式组和结构化活动组的活动调整后平均变化(95%置信区间[CIs])分别为0.84(95%CI,0.42 - 1.25千卡/千克/天;P<.001)和0.69(95%CI,0.25 - 1.12千卡/千克/天;P = .002),VO2peak分别为0.77(95%CI,0.18 - 1.36毫升/千克/分钟;P = .01)和1.34(95%CI,0.72 - 1.96毫升/千克/分钟;P<.001)。生活方式组和结构化活动组的收缩压(-3.63[95%CI,-5.54至-1.72毫米汞柱;P<.001]和-3.26[95%CI,-5.26至-1.25毫米汞柱;P = .002])和舒张压(-5.38[95%CI,-6.90至-3.86毫米汞柱;P<.001]和-5.14[95%CI,-6.73至-3.54毫米汞柱;P<.001])均有显著且相当的降低。两组体重均无显著变化(-0.05[95%CI,-1.05至0.96千克;P = .93]和0.69[95%CI,-0.37至1.74千克;P = .20]),但生活方式组和结构化活动组的体脂百分比均显著降低(分别为-2.39%[95%CI,-2.92%至-1.85%;P<.001]和-1.85%[95%CI,-2.41%至-1.28%;P<.001])。

结论

在既往久坐的健康成年人中,生活方式身体活动干预在改善身体活动、心肺适能和血压方面与结构化运动计划同样有效。

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