多囊卵巢综合征和母体肥胖会影响体外受精/胞浆内单精子注射周期中的卵母细胞大小。
Polycystic ovary syndrome and maternal obesity affect oocyte size in in vitro fertilization/intracytoplasmic sperm injection cycles.
机构信息
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri 63108, USA.
出版信息
Fertil Steril. 2011 May;95(6):2146-9, 2149.e1. doi: 10.1016/j.fertnstert.2010.10.026. Epub 2010 Nov 11.
Abstract
To determine the impact of maternal metabolic state on oocyte development in women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), we retrospectively analyzed a cohort of women with PCOS undergoing IVF/ICSI from 2008-2009 in a university-based fertility center. We determined that women with PCOS and obesity have smaller oocytes than control subjects, and that when further subdivided by body mass index, both PCOS and obesity independently influence oocyte size.
摘要
为了确定母体代谢状态对接受体外受精/胞浆内单精子注射（IVF/ICSI）的女性卵母细胞发育的影响，我们回顾性分析了 2008-2009 年在一家大学生育中心接受 IVF/ICSI 的多囊卵巢综合征（PCOS）女性的队列。我们发现，肥胖的 PCOS 女性的卵母细胞比对照组小，而当进一步按体重指数细分时，PCOS 和肥胖均独立影响卵母细胞大小。
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本文引用的文献
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Oocyte diameter as a predictor of fertilization and embryo quality in assisted reproduction cycles.卵母细胞直径作为辅助生殖周期中受精和胚胎质量的预测指标。
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