Shirakawa Sachiyo, Matsumoto Ippei, Nakayama Syunji, Mukubo Hideyo, Toyama Hirochika, Shinzeki Makoto, Fukumoto Takumi, Ajiki Tetsuo, Ku Yonson
Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine.
Nihon Shokakibyo Gakkai Zasshi. 2010 Nov;107(11):1828-34.
Pancreatic neoplasms during pregnancy are rare. We describe two cases of mucinous cystic neoplasm (MCN) associated with pregnancy. A 34-year-old woman in the 26th week of pregnancy was given a diagnosis of MCN measuring 19 cm in diameter. We decided to resect it post partum in consideration of the risk of abortion. She had a healthy infant in the 40th week of pregnancy and three months later, distal pancreatectomy was performed. Pathological analysis revealed a mucinous cystadenoma of the pancreas. The second case was a 36-year-old woman. She was given a diagnosis of MCN, measuring 16 cm in diameter, post partum and distal pancreatectomy was performed. Pathologically, the tumor was an invasive mucinous cystadenocarcinoma of the pancreas. In this report, we did an extensive literature review and discussed the management of MCN during pregnancy with special reference to the timing of the operation and the relationship between tumor growth and sex hormones.
孕期胰腺肿瘤较为罕见。我们描述了两例与妊娠相关的黏液性囊性肿瘤（MCN）。一名怀孕26周的34岁女性被诊断为直径19厘米的MCN。考虑到流产风险，我们决定在产后切除肿瘤。她在怀孕40周时产下一名健康婴儿，三个月后进行了胰腺远端切除术。病理分析显示为胰腺黏液性囊腺瘤。第二例是一名36岁女性。她在产后被诊断为直径16厘米的MCN，并接受了胰腺远端切除术。病理检查显示该肿瘤为胰腺浸润性黏液性囊腺癌。在本报告中，我们进行了广泛的文献综述，并讨论了孕期MCN的管理，特别提及手术时机以及肿瘤生长与性激素之间的关系。
