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使用脱蛋白马源骨矿物质进行牙槽窝保存。

Socket preservation using deproteinized horse-derived bone mineral.

作者信息

Park Jang-Yeol, Koo Ki-Tae, Kim Tae-Il, Seol Yang-Jo, Lee Yong-Moo, Ku Young, Rhyu In-Chul, Chung Chong-Pyoung

机构信息

Department of Periodontology and Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.

出版信息

J Periodontal Implant Sci. 2010 Oct;40(5):227-31. doi: 10.5051/jpis.2010.40.5.227. Epub 2010 Oct 31.

DOI:10.5051/jpis.2010.40.5.227
PMID:21072219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2967810/
Abstract

PURPOSE

The healing process following tooth extraction apparently results in a pronounced resorption of the alveolar ridge. As a result, the width of alveolar ridge is reduced and severe alveolar bone resorption occurs. The purpose of this experiment is to clinically and histologically evaluate the results of using horse-derived bone mineral for socket preservation.

METHODS

The study comprised 4 patients who were scheduled for extraction as a consequence of severe chronic periodontitis or apical lesion. The extraction was followed by socket preservation using horse-derived bone minerals. Clinical parameters included buccal-palatal width, mid-buccal crest height, and mid-palatal crest height. A histologic examination was conducted.

RESULTS

The surgical sites healed uneventfully. The mean ridge width was 7.75 ± 2.75 mm at baseline and 7.00 ± 2.45 mm at 6 months. The ridge width exhibited no significant difference between baseline and 6 months. The mean buccal crest height at baseline was 7.5 ± 5.20 mm, and at 6 months, 3.50 ± 0.58 mm. The mean palatal crest height at baseline was 7.75 ± 3.10 mm, and at 6 months, 5.00 ± 0.82 mm. There were no significant differences between baseline and 6 months regarding buccal and palatal crest heights. The amount of newly formed bone was 9.88 ± 2.90%, the amount of graft particles was 42.62 ± 6.57%, and the amount of soft tissue was 47.50 ± 9.28%.

CONCLUSIONS

Socket preservation using horse-derived bone mineral can effectively maintain ridge dimensions following tooth extraction and can promote new bone formation through osteoconductive activities.

摘要

目的

拔牙后的愈合过程显然会导致牙槽嵴明显吸收。结果,牙槽嵴宽度减小,出现严重的牙槽骨吸收。本实验的目的是从临床和组织学角度评估使用马源骨矿物质进行牙槽窝保存的效果。

方法

该研究纳入了4例因重度慢性牙周炎或根尖病变而计划拔牙的患者。拔牙后使用马源骨矿物质进行牙槽窝保存。临床参数包括颊腭宽度、颊侧牙槽嵴顶高度和腭侧牙槽嵴顶高度。进行了组织学检查。

结果

手术部位愈合顺利。基线时平均牙槽嵴宽度为7.75±2.75mm,6个月时为7.00±2.45mm。基线和6个月时牙槽嵴宽度无显著差异。基线时平均颊侧牙槽嵴顶高度为7.5±5.20mm,6个月时为3.50±0.58mm。基线时平均腭侧牙槽嵴顶高度为7.75±3.10mm,6个月时为5.00±0.82mm。颊侧和腭侧牙槽嵴顶高度在基线和6个月时无显著差异。新形成骨的量为9.88±2.90%,移植颗粒的量为42.62±6.57%,软组织的量为47.50±9.28%。

结论

使用马源骨矿物质进行牙槽窝保存可有效维持拔牙后牙槽嵴尺寸,并可通过骨传导活性促进新骨形成。

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本文引用的文献

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Ridge preservation techniques for implant therapy.种植体治疗的牙槽嵴保存技术。
Int J Oral Maxillofac Implants. 2009;24 Suppl:260-71.
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Comparative histomorphometric analysis of extraction sockets healing implanted with bovine xenografts, irradiated cancellous allografts, and solvent-dehydrated allografts in humans.人植入牛异种移植物、辐照松质骨同种异体移植物和溶剂脱水同种异体移植物后拔牙窝愈合的比较组织形态计量学分析
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The influence of Bio-Oss Collagen on healing of an extraction socket: an experimental study in the dog.
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使用接种骨髓间充质干细胞的改良异种脱蛋白骨修复骨缺损。
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Comparison of an allograft in an experimental putty carrier and a bovine-derived xenograft used in ridge preservation: a clinical and histologic study in humans.实验性油灰载体中的同种异体移植物与用于牙槽嵴保存的牛源异种移植物的比较:一项人体临床和组织学研究。
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